| Name | gamma glutamyltransferase |
|---|---|
| Synonyms | CD224; CD224 antigen; D22S672; D22S732; GGT; GGT 1; GGT1; GGT1 protein… |
| Name | HCH |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6191977 | Ito N, Tsuda H, Hasegawa R, Imaida K: Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. Environ Health Perspect. 1983 Apr;50:131-8. Of the miscellaneous compounds tested, phenobarbital, and ethynyl also induced gamma-glutamyl transpeptidase (gamma-GT) positive foci. |
3(0,0,0,3) | Details |
| 7532877 | Luebeck EG, Grasl-Kraupp B, Timmermann-Trosiener I, Bursch W, Schulte-Hermann R, Moolgavkar SH: Growth kinetics of enzyme-altered liver foci in rats treated with phenobarbital or alpha-hexachlorocyclohexane. Toxicol Appl Pharmacol. 1995 Feb;130(2):304-15. A quantitative method based upon a stochastic model for the appearance of initiated cells and their clonal growth was used to estimate cell birth and death rates in enzyme-altered liver foci (EAF). gamma-Glutamyltranspeptidase (gamma-GT)-positive foci were initiated in livers of female SPF Wistar rats by a single application of N-nitrosomorpholine. |
2(0,0,0,2) | Details |
| 18940228 | Anilakumar KR, Saritha V, Khanum F, Bawa AS: Ameliorative effect of ajwain extract on hexachlorocyclohexane-induced lipid peroxidation in rat liver. Food Chem Toxicol. 2009 Feb;47(2):279-82. Epub 2008 Oct 4. Prefeeding of ajwain extract at 1% level to rats injected with HCH reverted the significant changes in catalase, G-6-PDH, GST and -glutamyl transpeptidase. |
1(0,0,0,1) | Details |
| 7691758 | Nigam SK, Karnik AB, Chattopadhyay P, Lakkad BC, Venkaiah K, Kashyap SK: Clinical and biochemical investigations to evolve early diagnosis in workers involved in the manufacture of hexachlorocyclohexane. Int Arch Occup Environ Health. 1993;65(1 Suppl):S193-6. A significant positive correlation to liver related enzymes gamma GT, LAP and Alp. |
1(0,0,0,1) | Details |
| 2431769 | Schroter C, Parzefall W, Schroter H, Schulte-Hermann R: Dose-response studies on the effects of alpha-, beta-, and gamma-hexachlorocyclohexane on putative preneoplastic foci, monooxygenases, and growth in rat liver. Cancer Res. 1987 Jan 1;47(1):80-8. Foci were identified by means of the gamma-glutamyltransferase (GGT) reaction and by morphological alterations. |
1(0,0,0,1) | Details |
| 2427192 | Hasegawa R, Tsuda H, Shirai T, Kurata Y, Masuda A, Ito N: Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. Cancer Lett. 1986 Jul;32(1):15-23. The size of gamma-glutamyl transpeptidase positive foci was largest when PH was performed 1-3 weeks after the start of chemical feeding. |
1(0,0,0,1) | Details |
| 1691053 | Gerbracht U, Bursch W, Kraus P, Putz B, Reinacher M, Timmermann-Trosiener I, Schulte-Hermann R: Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver. Carcinogenesis. 1990 Apr;11(4):617-24. Foci were identified by a positive reaction for gamma-glutamyl-transpeptidase (GGT) and other cytological markers. |
1(0,0,0,1) | Details |
| 8519523 | Prasad AK, Pant N, Srivastava SC, Kumar R, Srivastava SP: Effect of dermal application of hexachlorocyclohexane (HCH) on male reproductive system of rat. Hum Exp Toxicol. 1995 Jun;14(6):484-8. The results indicate that exposure of HCH through the dermal route could lead to an alteration in the activities of marker testicular enzymes viz. sorbitol dehydrogenase (SDH), -6-P-dehydrogenase (G6PDH), gamma-glutamyl transpeptidase (gamma-GT) and beta-glucuronidase (beta Gluc.) associated with specific cell types. 3. |
1(0,0,0,1) | Details |
| 15501386 | Pant N, Mathur N, Banerjee AK, Srivastava SP, Saxena DK: Correlation of chlorinated pesticides concentration in semen with seminal vesicle and prostatic markers. Reprod Toxicol. 2004 Dec;19(2):209-14. An elevation in the level along with decrease in the gamma-glutamyl transpeptidase and acid phosphatase activity was noticed in infertile men as compared to fertile subjects. |
1(0,0,0,1) | Details |
| 2430350 | Kashyap SK: Health surveillance and biological monitoring of pesticide formulators in India. Toxicol Lett. 1986 Oct;33(1-3):107-14. Changes in the liver enzymes carbamyl transferase (OCT), gamma-glutamyl transpeptidase (GGTP), leucine aminopeptidase (LAP) and in immunoglobulin M (IgM) showed possible effects on liver and humoral immunity. |
1(0,0,0,1) | Details |
| 2873904 | Reinacher M, Eigenbrodt E, Gerbracht U, Zenk G, Timmermann-Trosiener I, Bentley P, Waechter F, Schulte-Hermann R: kinase isoenzymes in altered foci and carcinoma of rat liver. . Carcinogenesis. 1986 Aug;7(8):1351-7. Most L-PK- foci showed increases in gamma-glutamyltransferase (gamma-GT) and epoxide hydrolase (EH). |
1(0,0,0,1) | Details |