Name | superoxide dismutase |
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Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
Name | HCH |
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CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
PubMed | Abstract | RScore(About this table) | |
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9763530 | Kurose I, Wolf RE, Grisham MB, Granger DN: Hypercholesterolemia enhances oxidant production in mesenteric venules exposed to Ischemia/Reperfusion. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1583-8. Treatment with either or superoxide dismutase largely prevented the leukocyte recruitment, platelet-leukocyte aggregation, mast cell degranulation, and enhanced DHR oxidation elicited by I/R in HCh rats. |
31(0,1,1,1) | Details |
12038708 | Iscan M, Coban T, Cok I, Bulbul D, Eke BC, Burgaz S: The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association?. Breast Cancer Res Treat. 2002 Mar;72(2):173-82. The levels of some organochlorine pesticides (OCP) s (hexachlorobenzene, HCB, alpha-hexachlorocyclohexane, alpha-HCH, beta-HCH, gamma-HCH, heptachlorepoxide, HE, bis (4-chlorophenyl)-1,1-dichloroethene, p.p'DDE, bis (4-chlorophenyl)-1,1,1-trichloroethane, p.p' DDT and total DDT (E-DDT) and antioxidant enzyme activities namely Cu, Zn superoxide dismutase (SOD), catalase (CAT), -dependent peroxidase (Se- -Px), total peroxidase (T- -Px), independent peroxidase -Px II), glutathione reductase (GRd), level of and lipid peroxidation (LP), glutathione S-transferase (GST) activity toward several substrates including 1-chloro-2,4-dinitrobenzene (CDNB), 1,2-dichloro-4-nitrobenzene (DCNB), ethacrynic acid (EAA), 1,2-epoxy-3-(p-nitrophenoxy)-propane (ENPP) were measured in tumor and surrounding tumor free tissues of 24 female breast cancer patients and was evaluated whether there exist any association between the levels of OCPs and antioxidants. |
31(0,1,1,1) | Details |
11827286 | Sinha S: Oxidative stress induced by HCH in Hydrilla verticillata (l.f.) Royle: modulation in uptake and toxicity due to Fe. Chemosphere. 2002 Jan;46(2):281-8. The effect of HCH was also studied on and oxidised) content and superoxide dismutase activity. |
2(0,0,0,2) | Details |
16181528 | Liu H, Zhang GP, Song SJ, Ding MP, Zhou JF, Bie XD, Liu JR, Zhang Y, Li ZH, Gao HF, Liu GG, Fei LT: [Clinical study on Zhuyu Tongfu serial recipe combined with acupuncture and massotherapy in treating hypertensive cerebral hemorrhage.]. Chin J Integr Med. 2005 Sep;11(3):167-72. OBJECTIVE: To observe the clinical efficacy and mechanism of Zhuyu Tongfu (ZYTF) Serial Recipe combined with acupuncture and massotherapy in treating hypertensive cerebral hemorrhage (HCH). METHODS: One hundred and eighteen patients with hypertensive cerebral hemorrhage, on the basis of conventional Western medicine treatment, were randomly divided into ZYTF combined with acupuncture and massotherapy group (treated group) and simple Western medicine group (control group); the clinical efficacy, neurofunction deficit scoring (NDS) alterations and hematoma absorption rate of both groups were observed, and also the plasma superoxide dismutase (SOD) activity, plasma lipid peroxidase (LPO) content, erythrocyte peroxidase -Px) activity, hematocrit (Ht) and the whole blood viscosity (Va) change were also observed. |
1(0,0,0,1) | Details |
9467884 | Samanta L, Chainy GB: Comparison of hexachlorocyclohexane-induced oxidative stress in the testis of immature and adult rats. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1997 Nov;118(3):319-27. Activities of testicular cytosolic superoxide dismutases (total and CN (-)-resistant) of rats of 15- and 90-day-old age groups decreased significantly after 6 hr of HCH treatment, and remained decreased till 24 hr of the pesticide treatment. |
1(0,0,0,1) | Details |
18940228 | Anilakumar KR, Saritha V, Khanum F, Bawa AS: Ameliorative effect of ajwain extract on hexachlorocyclohexane-induced lipid peroxidation in rat liver. Food Chem Toxicol. 2009 Feb;47(2):279-82. Epub 2008 Oct 4. Results revealed that HCH administration lead to an increase in hepatic lipid peroxidation associated with reduction in, levels of (GSH), activity of superoxide dismutase (SOD), catalase and glucose-6-phosphate dehydrogenase. |
1(0,0,0,1) | Details |
1708174 | Barros SB, Simizu K, Junqueira VB: Liver lipid peroxidation-related parameters after short-term administration of hexachlorocyclohexane isomers to rats. Toxicol Lett. 1991 Apr;56(1-2):137-44. In these animals superoxide dismutase (SOD) activity was also increased. |
1(0,0,0,1) | Details |
17123163 | Anilakumar KR, Khanum F, Santhanam K: Amelioration of hexachlorocyclohexane-induced oxidative stress by amaranth leaves in rats. Plant Foods Hum Nutr. 2006 Dec;61(4):169-73. Amaranth leaves at 10 and 20% levels of feeding reduced the hepatic superoxide dismutase and peroxidase (GSH-Px) activities. |
1(0,0,0,1) | Details |
7538972 | Samanta L, Chainy GB: Hexachlorocyclohexane-induced changes in lipid peroxidation, superoxide dismutase and catalase activities and content in chick liver. Indian J Exp Biol. 1995 Feb;33(2):131-3. |
1(0,0,0,1) | Details |
10350190 | Samanta L, Sahoo A, Chainy GB: Age-related changes in rat testicular oxidative stress parameters by hexachlorocyclohexane. Arch Toxicol. 1999 Mar;73(2):96-107. In both age-groups of rats, the pesticide elicited a significant decrease in the activities of cytosolic superoxide dismutase (SOD; total and CN (-)-resistant) and catalase, and content together with an increase in the levels of LPX (both in crude homogenate and subcellular fractions) and H2O2. |
1(0,0,0,1) | Details |
16838206 | Wang F, Xu ZR, Sun JH: Effect of HCH contamination of diet on the growth performance and immune and antioxidant ability in growing/finishing pigs. Vet Res Commun. 2006 Aug;30(6):645-54. Addition of HCH to feedstuff reduced superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione reductase (GR) and peroxidase (GSH-Px) activities in liver, reduced serum catalase (CAT) activity, and increased serum malondialehyde (MDA). |
1(0,0,0,1) | Details |
8546756 | Araujo FB, Barbosa DS, Hsin CY, Maranhao RC, Abdalla DS: Evaluation of oxidative stress in patients with hyperlipidemia. . Atherosclerosis. 1995 Sep;117(1):61-71. HLP had lower plasma superoxide dismutase (SOD) activity (0.04 and 0.11 U/mg protein; P < 0.05) as well as lower concentrations of (0.1 and 0.2 nmol/mg P < 0.05) and (0.8 and 2.7 nmol/mg P < 0.05) in the plasma, as compared with NL. |
1(0,0,0,1) | Details |
16046044 | Srivastava A, Shivanandappa T: Hexachlorocyclohexane differentially alters the antioxidant status of the brain regions in rat. Toxicology. 2005 Oct 15;214(1-2):123-30. Activities of peroxidase, glutathione reductase, glutathione-S-transferase and catalase were markedly induced whereas superoxide dismutase was inhibited at higher dose in all the brain regions. |
1(0,0,0,1) | Details |
9704597 | Sahoo A, Chainy GB: Acute hexachlorocyclohexane-induced oxidative stress in rat cerebral hemisphere. Neurochem Res. 1998 Aug;23(8):1079-84. The pesticide elicited decrease in the activities of cytosolic total, CN (-)-sensitive (not at 24 h) and CN-resistant superoxide dismutases; total, Se-dependent and Se-independent peroxidases; and catalase throughout the measurement period. |
1(0,0,0,1) | Details |
12364975 | Samanta L, Chainy GB: Response of testicular antioxidant enzymes to hexachlorocyclohexane is species specific. Asian J Androl. 2002 Sep;4(3):191-4. Similarly, the decreased activity of superoxide dismutase observed in rats remained unaltered in mice. |
1(0,0,0,1) | Details |
2299401 | Saltarelli MD, Yamada K, Coyle JT: Phospholipase A2 and 3H-hemicholinium-3 binding sites in rat brain: a potential second-messenger role for fatty acids in the regulation of high-affinity uptake. J Neurosci. 1990 Jan;10(1):62-72. The involvement of phospholipase A2 (PLA2) and fatty acid release in the regulation of -dependent high-affinity uptake in rat brain was assessed in vitro through the use of the specific binding of 3H-hemicholinium-3 (3H-HCh-3). |
0(0,0,0,0) | Details |