| Name | ATPase |
|---|---|
| Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
| Name | HCH |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7532328 | Srivastava SC, Kumar R, Prasad AK, Srivastava SP: Effect of hexachlorocyclohexane (HCH) on testicular plasma membrane of rat. Toxicol Lett. 1995 Jan;75(1-3):153-7. The results indicate inhibition in the activity of the Ca (2+)-ATPase, Na (+)+K (+)+Mg (2+)-ATPase and 5'Nucleotidase. |
1(0,0,0,1) | Details |
| 3157412 | Timofeev AA, Azizova OA, Chernysheva GV: [Role of lipid peroxidation in changes in the structure of Ca-ATPase in skeletal muscle sarcoplasmic reticulum during hypercholesterolemia]. Biull Eksp Biol Med. 1985 Mar;99(3):301-3. Using the method of spin labels it was shown that in hypercholesterolemia (HCh), the following parameters decreased: the velocity of maleimide spin label binding to sarcoplasmic reticulum (SR) Ca-ATPase of rabbit skeletal muscles, the accessibility of spin-labeled thiol groups of the enzyme to ferricyanide and and the mobility of the Ca-ATPase molecule fragment to which the spin label was attached. |
163(2,2,2,3) | Details |
| 8997551 | Kristofikova Z, Klaschka J: In vitro effect of Ginkgo biloba extract (EGb 761) on the activity of presynaptic cholinergic nerve terminals in rat hippocampus. Dement Geriatr Cogn Disord. 1997 Jan-Feb;8(1):43-8. The effects of Ginkgo biloba extract (EGb) applied in vitro to hippocampal synaptosomes from young Wistar rats on the specific binding of [3H] hemicholinium-3 ([3H] HCh-3), high-affinity uptake (HACU) and activity of Na+,K (+)-ATPase were examined. |
81(1,1,1,1) | Details |
| 9021765 | Kristofikova Z, Klaschka J: In vitro effects of arachidonic and L-glutamic acids on the high-affinity transport in rat hippocampus. Neurochem Res. 1997 Jan;22(1):67-73. Millimolar concentrations of GA decrease both the high- and low-affinity uptake, the specific as well as nonspecific binding of [3H] HCh-3 and the activity of Na+, K (+)-ATPase. |
31(0,1,1,1) | Details |
| 9989472 | Sahoo A, Samanta L, Das A, Patra SK, Chainy GB: Hexachlorocyclohexane-induced behavioural and neurochemical changes in rat. J Appl Toxicol. 1999 Jan-Feb;19(1):13-8. Effect of chronic oral exposure (10 and 20 mg kg (-1) body wt. for 7, 15 and 30 days) to hexachlorocyclohexane (HCH) on open-field behaviour and activities of cerebral Na+,K+-ATPase, Mg2+-ATPase and acetylcholinesterase (AChE) of rat was evaluated. |
7(0,0,1,2) | Details |
| 9026152 | Roy A, Chainy GB: Age-related change in rat testicular ATPase activities in response to HCH treatment. Bull Environ Contam Toxicol. 1996 Jan;56(1):165-70. |
6(0,0,1,1) | Details |
| 1839160 | Ahmed MT, Ismail SM: Residues of organochlorine pesticides in fish, crab and sediment from El Temsah Lake, Suez Canal, Egypt and their effect on mitochondrial ATPase of the New Zealand white rabbit. J Egypt Public Health Assoc. 1991;66(5-6):557-75. The In-vitro effect of the residues extracted from fish, and crab on the mitochondrial brain and liver ATPase of the New Zealand white rabbit Orcytolagus cuniculus was also studied. |
3(0,0,0,3) | Details |
| 16432761 | Srivastava A, Shivanandappa T: Causal relationship between hexachlorocyclohexane cytotoxicity, oxidative stress and Na+, K +-ATPase in Ehrlich Ascites tumor cells. Mol Cell Biochem. 2006 Jun;286(1-2):87-93. Epub 2006 Jan 24. |
3(0,0,0,3) | Details |
| 19818741 | Srivastava A, Shivanandappa T: Stereospecificity in the cytotoxic action of hexachlorocyclohexane isomers. Chem Biol Interact. 2010 Jan 5;183(1):34-9. Epub . HCH inhibited Na (+),K (+)-ATPase, which could be involved in raising the intracellular and increased Ca (2+),Mg (2+)-ATPase activity. |
2(0,0,0,2) | Details |
| 7685730 | Agrawal D, Sultana P: Biochemical and structural alterations in rat erythrocytes due to hexachlorocyclohexane exposure. Food Chem Toxicol. 1993 Jun;31(6):443-8. The changes in biochemical constituents of rat erythrocyte membranes were observed after a single ip exposure to 300 mg commercial HCH/kg body weight (one-third of the LD50). The phospholipid:cholesterol ratio was altered, and there were changes in the activities of the membrane-bound enzymes ATPase and acetylcholinesterase. |
2(0,0,0,2) | Details |
| 7594191 | Anand M, Meera P, Kumar R, Gupta GS, Tripathi O, Srimal RC: Possible role of in the cardiovascular effects of prolonged administration of gamma-HCH (lindane) in rats. J Appl Toxicol. 1995 Jul-Aug;15(4):245-8. The plasma concentration was increased (32%) and Ca,K-ATPase activity in heart was decreased (50%). |
1(0,0,0,1) | Details |
| 17369300 | Endo R, Ohtsubo Y, Tsuda M, Nagata Y: Identification and characterization of genes encoding a putative ABC-type transporter essential for utilization of gamma-hexachlorocyclohexane in Sphingobium japonicum UT26. J Bacteriol. 2007 May;189(10):3712-20. Epub 2007 Mar 16. This putative ABC transporter consists of four components, permease, ATPase, periplasmic protein, and lipoprotein, encoded by linK, linL, linM, and linN, respectively. |
1(0,0,0,1) | Details |
| 9865422 | Bhalla P, Agrawal D: Alterations in rat erythrocyte membrane due to hexachlorocyclohexane (technical) exposure. Hum Exp Toxicol. 1998 Nov;17(11):638-42. Administration of HCH (technical) to rats at 5 mg/kg, orally, 5 days a week for 1, 2 and 3 months caused marked increase in erythrocyte membrane fluidity, osmotic fragility and decrease in levels of Na+, K (+)-ATPase, acetylcholinesterase in erythrocytes and in blood. 2. |
1(0,0,0,1) | Details |
| 2461408 | Srinivasan K, Radhakrishnamurty R: Biochemical changes produced by beta- and gamma-hexachlorocyclohexane isomers in albino rats. J Environ Sci Health B. 1988 Aug;23(4):367-86. An unaltered ratio of DNP/Mg++-ATPase, a study of swelling pattern of hepatic mitochondria, and NAD+ permeability test suggested the maintenance of structural integrity of mitochondrial membrane in these pesticide fed animals. |
1(0,0,0,1) | Details |