Protein Information

Name beta is
Synonyms "beta I"; Alpha II; Alpha tryptase; Beta I; Lung tryptase; Mast cell protease II; Mast cell tryptase; Pituitary tryptase…

Compound Information

Name gamma-HCH
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
18996566 Zamir R, Athanasiadou M, Nahar N, Mamun MI, Mosihuzzaman M, Bergman A: Persistent organohalogen contaminants in plasma from groups of humans with different occupations in Bangladesh. Chemosphere. 2009 Jan;74(3):453-9. Epub 2008 Nov 8.


Among the other pesticides analysed beta-HCH is the most abundant indicating the use of technical HCH products instead of Lindane (gamma-HCH).
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9299729 Otero R, Santiago-Silva M, Grimalt JO: Hexachlorocyclohexanes in human blood serum. J Chromatogr A. 1997 Aug 22;778(1-2):87-94.


The results have shown that beta-HCH is selectively accumulated in human sera and prompt to the preferential investigation of the toxic effects of this isomer in humans and mammals.
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20199797 Hedley AJ, Hui LL, Kypke K, Malisch R, van Leeuwen FX, Moy G, Wong TW, Nelson EA: Residues of persistent organic pollutants (POPs) in human milk in Hong Kong. Chemosphere. 2010 Apr;79(3):259-65. Epub 2010 Mar 2.


Continuous monitoring of POPs in human milk, especially beta-HCH, is needed for surveillance and interpretation of time trends, and for linkage to strict enforcement of agricultural regulations.
1(0,0,0,1) Details
17516046 Ito M, Prokop Z, Klvana M, Otsubo Y, Tsuda M, Damborsky J, Nagata Y: Degradation of beta-hexachlorocyclohexane by haloalkane dehalogenase LinB from gamma-hexachlorocyclohexane-utilizing bacterium Sphingobium sp. Arch Microbiol. 2007 Oct;188(4):313-25. Epub 2007 May 22.


The technical formulation of hexachlorocyclohexane (HCH) mainly consists of the insecticidal gamma-isomer and noninsecticidal alpha-, beta-, and delta-isomers, among which beta-HCH is the most recalcitrant and has caused serious environmental problems.
1(0,0,0,1) Details