Name | cytochrome P450 monooxygenases |
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Synonyms | CYP M; CYP20A1; CYP20A1 protein; Cytochrome P450 family 20 subfamily A polypeptide 1; Cytochrome P450 monooxygenase; CYP20A1 proteins; Cytochrome P450 family 20 subfamily A polypeptide 1s; Cytochrome P450 monooxygenases |
Name | aldrin |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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1375920 | Foster JR, Green T, Smith LL, Lewis RW, Hext PM, Wyatt I: Methylene lungs of mice over an exposure period of 90 days. Fundam Appl Toxicol. 1992 Apr;18(3):376-88. The appearance and disappearance of the lesion in the Clara cell correlated well with the activity of cytochrome P450 monooxygenase in the Clara cell as assessed immunocytochemically (cytochromes P450IIB 1 and 2) in the whole lung and biochemically in the freshly isolated Clara cell (determined by ethoxycoumarin O-dealkylation and aldrin epoxidation). |
--an inhalation study to investigate pathological and biochemical events occurring in the 31(0,1,1,1) | Details |
20050562 | Xiao NW, Liu XH, Li W, Ge F: Effect of herbicide acetochlor on cytochrome P450 monooxygenases and GST of earthworms Eisenia fetida. J Environ Sci. 2006;18(1):135-40. Effects of the acetochlor on cytochrome P450 monooxygenases p-nitroanisole O-demethylase (ODM), aldrin epoxidase (AE) and glutathione-S-transferases (GSTs) activities were determined. |
8(0,0,1,3) | Details |
9076527 | Kotze AC: Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda). Int J Parasitol. 1997 Jan;27(1):33-40. Cytochrome P450 monooxygenase activities towards aldrin and 7-ethoxycoumarin were detected in microsomes prepared from L1 and L3 larvae of Haemonchus contortus, and very low levels of activity towards aldrin were detected in adults. |
8(0,0,1,3) | Details |
14503602 | Qiu X, Li W, Tian Y, Leng X: Cytochrome P450 monooxygenases in the cotton bollworm (Lepidoptera: Noctuidae): tissue difference and induction. J Econ Entomol. 2003 Aug;96(4):1283-9. Orthogonal array design was used to establish the optimal conditions for measuring Aldrin epoxidation (AE). |
1(0,0,0,1) | Details |
18432628 | Krieger RI: Aldrin epoxidation and dihydroisodrin hydroxylation as probes of in vivo and in vitro oxidative metabolic capability of some caterpillars. Pest Manag Sci. 2008 Jun;64(6):622-7. Localization of relatively high concentrations of these cytochrome P450 monooxygenases in gut tissue of lepidoptera may represent an important means to minimize absorption of lipophilic foreign chemicals in food. |
1(0,0,0,1) | Details |
18065401 | Rupasinghe SG, Wen Z, Chiu TL, Schuler MA: Helicoverpa zea CYP6B8 and CYP321A1: different molecular solutions to the problem of metabolizing plant toxins and insecticides. Protein Eng Des Sel. 2007 Dec;20(12):615-24. Epub 2007 Dec 6. Under continual exposure to naturally occurring plant toxins and synthetic insecticides, insects have evolved cytochrome P450 monooxygenases (P450s) capable of metabolizing a wide range of structurally different compounds. The metabolic profiles for several plant toxins (xanthotoxin, and insecticides (cypermethrin, aldrin and diazinon) correlate well with these predictive models. |
1(0,0,0,1) | Details |
11425027 | Lee SE, Lees EM: Biochemical mechanisms of resistance in strains of Oryzaephilus surinamensis (Coleoptera: Silvanidae) resistant to malathion and chlorpyrifos-methyl. J Econ Entomol. 2001 Jun;94(3):706-13. Cytochrome P450 monooxygenase activity was based on cytochrome P450 content, aldrin epoxidase activity, and oxidation of organophosphate insecticides, all elevated in resistant strains. |
32(0,1,1,2) | Details |