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aldrin

Identification (Source:EPA,EU)

ID	1472
Name	aldrin
CAS	309-00-2
IUPAC
Inchi	InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-
CIPAC	27
EPA Code	045101
Formula	C12H8Cl6
SMILES	Cl\C3=C(/Cl)C4(Cl)C2C(C1/C=C\C2C1)C3(Cl)C4(Cl)Cl
Status	Not Approved

Classification

Mode of Action	Central nervous system stimulant. GABA-gated chloride channel antagonist. Also stomach and contact toxin
Pesticide Type	Insecticide
Chemical Group	Cyclodiene
Classification	cyclodiene insecticides

Properties (Source:PubChem)

Molecular Weight	364.91
Physical State	White to brown crystals
AlogP	4.264
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	270.53
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic invertebrates	Acute	48 hour	EC50	0.028 mg l-1
Birds	Acute		LD50	6.6 mg kg-1
Earthworms	Acute	14 day	LD50	60 mg kg-1
Fish	Acute	96 hour	LC50	0.0046 mg l-1
Honeybees	Acute	48 hour	LD50	0.35 μg bee-1
Mammals	Acute oral		LD50	39 mg kg-1
	Bio-concentration factor		BCF	3348
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
cytochrome P450 (protein family or complex)	1947(14,25,76,242)	Details
ATPase	434(4,7,9,14)	Details
chloride channel (protein family or complex)	163(2,2,2,3)	Details
cytochrome c	175(1,3,7,15)	Details
ATPases	135(1,2,5,10)	Details
lactate dehydrogenase (protein family or complex)	83(1,1,1,3)	Details
progesterone receptors	82(1,1,1,2)	Details
GT1	82(1,1,1,2)	Details
demethylase	241(0,4,21,36)	Details
glutathione S transferase	144(0,2,13,29)	Details
epoxide hydrolase	125(0,2,10,25)	Details
cytochrome P450 monooxygenases	82(0,2,4,12)	Details
Microsomal monooxygenase	63(0,1,4,18)	Details
aryl hydrocarbon hydroxylase	59(0,1,5,9)	Details
glucagon	43(0,1,3,3)	Details
calmodulin	43(0,1,2,8)	Details
albumin	40(0,1,2,5)	Details
debrisoquine 4 hydroxylase	39(0,1,2,4)	Details
cholinesterases	37(0,1,1,7)	Details
P 450MP	36(0,1,1,6)	Details
brains	34(0,1,1,4)	Details
NMDA receptor (protein family or complex)	31(0,1,1,1)	Details
MC7	31(0,1,1,1)	Details
U82	31(0,1,1,1)	Details
chitinase	31(0,1,1,1)	Details
Basalin	31(0,1,1,1)	Details
transferase	32(0,0,4,12)	Details
Lipoxygenase (protein family or complex)	20(0,0,3,5)	Details
alkaline phosphatase	19(0,0,3,4)	Details
C18	16(0,0,1,11)	Details

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