Protein Information

Name caspase 3
Synonyms Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor…

Compound Information

Name deltamethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
15555316 Li T, Shi N, Zhong YF, Dong J, Chen L, Wang B, Chen D, Wei YH, Dai ZH: [Effects of deltamethrin on the apoptosis and the expression of caspase-3 in rat neural cells.]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2004 Oct;22(5):371-4.
21(0,0,3,6) Details
19326768 Das PC, Streit TM, Cao Y, Rose RL, Cherrington N, Ross MK, Wallace AD, Hodgson E: Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. Drug Metabol Drug Interact. 2008;23(3-4):211-36.

Dose-dependent induction of caspase-3/7 was initiated by 12.5 microM deltamethrin or by 3.125 microM permethrin.
7(0,0,1,2) Details
16644695 Ranta F, Avram D, Berchtold S, Dufer M, Drews G, Lang F, Ullrich S: Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes. 2006 May;55(5):1380-90.

In INS-1 cells, dexamethasone increased the number of transferase-mediated dUTP nick-end labeling-staining positive cells, caspase-3 activity, and poly-(ADP-) ribose polymerase protein cleavage; decreased Bcl-2 transcript and protein abundance; dephosphorylated the proapoptotic protein of the Bcl-2 family (BAD) at serine155; and depolarized mitochondria.
FK506 (0.1 micromol/l) and another calcineurin inhibitor, deltamethrin (1 micromol/l), attenuated dexamethasone-induced cell death.
1(0,0,0,1) Details