deltamethrin
Identification (Source:EPA,EU)
| ID |
1610 |
| Name |
deltamethrin |
| CAS |
52918-63-5 |
| IUPAC |
|
| Inchi |
InChI=1S/C22H19Br2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17-,18+,20-/m0/s1 |
| CIPAC |
333 |
| EPA Code |
978051 |
| Formula |
C22H19Br2NO3 |
| SMILES |
Br/C(Br)=C/[C@H]3[C@@H](C(=O)O[C@H](C#N)c2cccc(Oc1ccccc1)c2)C3(C)C |
| Status |
Approved |
Classification
| Mode of Action |
Non-systemic with contact and stomach action. Sodium channel modulator. |
| Pesticide Type |
Insecticide, Metabolite, Veterinary treatment |
| Chemical Group |
Pyrethroid |
| Classification |
pyrethroid ester insecticides
|
Properties (Source:PubChem)
| Molecular Weight |
505.2 |
| Physical State |
Colourless crystals |
| AlogP |
5.522 |
| H-Bond Donor |
0 |
| H-Bond Acceptor |
4 |
| Surface Area |
412.06 |
| Polar Surface Area |
59.32 |
Structure
Ecotoxicology (Source:PPDB,IPM)
| Species |
Method |
Study Time |
Dose Type |
Value |
| Algae |
Acute |
72 hour |
EC50, growth |
9.1 mg l-1 |
| Aquatic crustaceans |
Acute |
96 hour |
LC50 |
0.0000017 mg l-1 |
| Aquatic invertebrates |
Acute |
48 hour |
EC50 |
0.00056 mg l-1 |
| Aquatic invertebrates |
Chronic |
21 day |
NOEC |
0.0041 mg l-1 |
| Birds |
Acute |
|
LD50 |
> 2250 mg kg-1 |
| Birds |
Short term dietary |
|
LC50/LD50 |
> 5620 ppm |
| Earthworms |
Acute |
14 day |
LD50 |
> 1290 mg kg-1 |
| Fish |
Acute |
96 hour |
LC50 |
0.00026 mg l-1 |
| Fish |
Chronic |
21 day |
NOEC |
< 0.032 mg l-1 |
| Honeybees |
Acute |
48 hour |
LD50 |
0.0015 μg bee-1 |
| Mammals |
Acute oral |
|
LD50 |
87 mg kg-1 |
| Mammals |
Short term dietary |
|
NOEL |
2.5 mg kg-1 |
| Sediment dwelling organisms |
Chronic |
28 day |
NOEC, sediment |
0.01 mg kg-1 |
|
Bio-concentration factor |
|
CT50 |
Not available days |
|
Bio-concentration factor |
|
BCF |
1400 |
Related targets
| Target Name |
RScore (About this table) |
|
|
sodium channel (protein family or complex)
|
1278(12,16,30,128) |
Details |
|
cytochrome P450 (protein family or complex)
|
842(8,10,27,57) |
Details |
|
calcineurin (protein family or complex)
|
797(6,14,14,77) |
Details |
|
Ca v
|
365(4,5,6,10) |
Details |
|
cis 3
|
316(3,5,6,11) |
Details |
|
Acetylcholinesterase
|
449(2,6,23,84) |
Details |
|
ATPase
|
241(2,3,9,21) |
Details |
|
bcl 2
|
233(2,3,9,13) |
Details |
|
cytochrome c
|
218(2,2,10,18) |
Details |
|
CYP1A1
|
186(2,2,5,11) |
Details |
|
glutamate receptor
|
163(2,2,2,3) |
Details |
|
calcineurin inhibitors
|
234(1,5,9,14) |
Details |
|
calmodulin
|
230(1,5,6,25) |
Details |
|
chloride channel (protein family or complex)
|
156(1,3,4,11) |
Details |
|
G protein
|
148(1,3,3,8) |
Details |
|
brain derived neurotrophic factor
|
154(1,2,8,14) |
Details |
|
tyrosine hydroxylase
|
137(1,2,5,12) |
Details |
|
Cytochrome c oxidase (protein family or complex)
|
127(1,2,4,7) |
Details |
|
GABA receptor (protein family or complex)
|
121(1,2,2,11) |
Details |
|
protein phosphatase
|
121(1,2,2,11) |
Details |
|
NF E2 related factor 2
|
101(1,1,4,6) |
Details |
|
somatostatin
|
97(1,1,2,12) |
Details |
|
CFTR
|
93(1,1,1,13) |
Details |
|
adenylate cyclase
|
90(1,1,2,5) |
Details |
|
CYP1A2
|
89(1,1,1,9) |
Details |
|
hCE 1
|
89(1,1,2,4) |
Details |
|
hemoglobin (protein family or complex)
|
88(1,1,2,3) |
Details |
|
monoamine oxidase
|
84(1,1,1,4) |
Details |
|
peripheral type benzodiazepine receptors
|
84(1,1,1,4) |
Details |
|
calcium channel (protein family or complex)
|
84(1,1,1,4) |
Details |
|
protein tyrosine phosphatases
|
83(1,1,1,3) |
Details |
|
CYP2D6
|
83(1,1,1,3) |
Details |
|
choline acetyltransferase
|
83(1,1,1,3) |
Details |
|
S100beta
|
81(1,1,1,1) |
Details |
|
somatotropins
|
81(1,1,1,1) |
Details |
|
synapsin I
|
81(1,1,1,1) |
Details |
|
BIII
|
81(1,1,1,1) |
Details |
|
aromatic l amino acid decarboxylase
|
81(1,1,1,1) |
Details |
|
IP2
|
81(1,1,1,1) |
Details |
|
NMDA receptor (protein family or complex)
|
129(0,4,4,9) |
Details |
|
CYP3A4
|
77(0,2,3,12) |
Details |
|
serine threonine protein phosphatase
|
63(0,2,2,3) |
Details |
|
Salvador
|
62(0,1,5,12) |
Details |
|
c fos
|
62(0,1,6,7) |
Details |
|
G6PD
|
60(0,1,4,15) |
Details |
|
Nav1.4
|
56(0,1,5,6) |
Details |
|
c jun
|
55(0,1,5,5) |
Details |
|
cytochrome P450 monooxygenase
|
50(0,1,3,10) |
Details |
|
PP2A
|
41(0,1,1,11) |
Details |
|
thrombin
|
36(0,1,1,6) |
Details |
|
glucagon
|
36(0,1,1,6) |
Details |
|
estrogen receptors
|
36(0,1,1,6) |
Details |
|
Ho 1
|
34(0,1,1,4) |
Details |
|
PPase
|
34(0,1,1,4) |
Details |
|
Camk1g
|
33(0,1,1,3) |
Details |
|
carboxylesterase 1
|
33(0,1,1,3) |
Details |
|
GABAT
|
33(0,1,1,3) |
Details |
|
hCE 2
|
32(0,1,1,2) |
Details |
|
CaM kinase II (protein family or complex)
|
32(0,1,1,2) |
Details |
|
cis 1
|
31(0,1,1,1) |
Details |
|
annexin V
|
31(0,1,1,1) |
Details |
|
Potassium channel (protein family or complex)
|
31(0,1,1,1) |
Details |
|
beta adrenoceptor (protein family or complex)
|
31(0,1,1,1) |
Details |
|
glutathione S transferase
|
49(0,0,2,39) |
Details |
|
P53
|
30(0,0,5,5) |
Details |
|
caspase 3
|
29(0,0,4,9) |
Details |
|
catalase
|
28(0,0,3,13) |
Details |
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