Name | Nav1.4 |
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Synonyms | HYKPP; HYPP; NAC1A; Na(V)1.4; Nav1.4; SCN4A; SkM1; Sodium channel protein type 4 subunit alpha… |
Name | deltamethrin |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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11502895 | Wang SY, Barile M, Wang GK: A Nav1.4 voltage-gated Na (+) channels is critical for pyrethroid action. Mol Pharmacol. 2001 Sep;60(3):620-8. A background mutation, Nav1.4-I687M (within D2:S4-S5 cytoplasmic linker), enhanced the deltamethrin-induced maintained current by approximately 2.5-fold, whereas Nav1.4-I687T, a homologous superkdr mutation, reduced it by approximately 2-fold. |
residue at segment D3-S6 in 56(0,1,5,6) | Details |