Protein Information

Name G protein
Synonyms G gamma I; Guanine nucleotide binding protein 2; G protein; GNG 2; GNG2; GNGT 2; GNGT2; Guanine nucleotide binding protein gamma 2…

Compound Information

Name deltamethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
11533141 Gromada J, Hoy M, Buschard K, Salehi A, Rorsman P: Somatostatin inhibits exocytosis in rat pancreatic alpha-cells by G (i2)-dependent activation of calcineurin and depriming of secretory granules. J Physiol. 2001 Sep 1;535(Pt 2):519-32.

The inhibitory effect of somatostatin on exocytosis was mediated by activation of the serine/threonine protein phosphatase calcineurin and was prevented by pretreatment with cyclosporin A and deltamethrin or intracellularly applied calcineurin autoinhibitory peptide.
The latter effect was mimicked by intracellular dialysis with specific antibodies to G (i1/2) and by antisense oligonucleotides against G proteins of the subtype G (i2). 4.
1(0,0,0,1) Details
10535451 Poulsen CR, Bokvist K, Olsen HL, Hoy M, Capito K, Gilon P, Gromada J: Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells. Diabetes. 1999 Nov;48(11):2171-81.

Inhibition of exocytosis by ATP resulted from G-protein-dependent activation of the serine/threonine protein phosphatase calcineurin and was abolished by cyclosporin A and deltamethrin.
81(1,1,1,1) Details
14563173 de Ondarza J, Symington SB, Van Houten JL, Clark JM: G-protein modulators alter the swimming behavior and calcium influx of Paramecium tetraurelia. J Eukaryot Microbiol. 2003 Sep-Oct;50(5):349-55.

To determine whether G-proteins exert their effect via the ciliary voltage-sensitive calcium channel, we examined responses of P. tetraurelia to the potent voltage-sensitive calcium channel agonist, deltamethrin.
66(0,2,2,6) Details