Name | somatostatin |
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Synonyms | Growth hormone release inhibiting factor; SMST; SST; Somatostatin; Somatostatin precursor; Somatostatins; Somatostatin precursors |
Name | deltamethrin |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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11533141 | Gromada J, Hoy M, Buschard K, Salehi A, Rorsman P: Somatostatin inhibits exocytosis in rat pancreatic alpha-cells by G (i2)-dependent activation of calcineurin and depriming of secretory granules. J Physiol. 2001 Sep 1;535(Pt 2):519-32. The inhibitory effect of somatostatin on exocytosis was mediated by activation of the serine/threonine protein phosphatase calcineurin and was prevented by pretreatment with cyclosporin A and deltamethrin or intracellularly applied calcineurin autoinhibitory peptide. |
89(1,1,1,9) | Details |
12044486 | Grosse G, Thiele T, Heuckendorf E, Schopp E, Merder S, Pickert G, Ahnert-Hilger G: Deltamethrin differentially affects neuronal subtypes in hippocampal primary culture. Neuroscience. 2002;112(1):233-41. When analyzing subtypes of neurons calbindin- as well as somatostatin-positive neurons decreased by 50% after repeated treatment with 2 nM deltamethrin. |
6(0,0,1,1) | Details |
10844399 | Kampermann J, Herbst M, Ullrich S: Effects of insulin secretion in INS-1 cells under voltage control. Cell Physiol Biochem. 2000;10(1-2):81-90. After incubation of the cells with deltamethrin, a calcineurin inhibitor, the stimulation of secretion was attenuated, but the -induced inhibition was not affected. The aim of the present study was to investigate whether mechanisms distal to the regulation of Ca2-influx are involved in -induced stimulation and - and somatostatin- induced inhibition of insulin secretion in INS-1 cells. |
and on 2(0,0,0,2) | Details |