| Name | bcl 2 |
|---|---|
| Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
| Name | deltamethrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12628584 | Wu A, Li L, Liu Y: Deltamethrin induces apoptotic cell death in cultured cerebral cortical neurons. Toxicol Appl Pharmacol. 2003 Feb 15;187(1):50-7. Western blot analysis demonstrated that p53 and Bax expression were dramatically increased at the same time points, whereas Bcl-2 expression was significantly reduced at all time points after deltamethrin treatment. |
112(1,2,2,2) | Details |
| 18724894 | Guo L, Sun M, Xu PP, Xu YP, Lu HP, Si HY, Yan H: [Effects of on nerve cell apoptosis and expression of Bcl-2 & cytochrome C genes in rat cerebrum with deltamethrin induction]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 Apr;26(4):215-8. CONCLUSION: MT can protect nerve cell against deltamethrin induced brain injury by inhibiting nerve cell apoptosis, downregulate the protein expression of cytochrome C gene and upregulate the protein expression of bcl-2 gene. |
95(1,1,3,5) | Details |
| 10771154 | Wu A, Ren T, Hu Q, Liu Y: Deltamethrin induces altered expression of P53, Bax and Bcl-2 in rat brain. Neurosci Lett. 2000 Apr 21;284(1-2):29-32. |
24(0,0,4,4) | Details |
| 16644695 | Ranta F, Avram D, Berchtold S, Dufer M, Drews G, Lang F, Ullrich S: Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes. 2006 May;55(5):1380-90. In INS-1 cells, dexamethasone increased the number of transferase-mediated nick-end labeling-staining positive cells, caspase-3 activity, and poly-(ADP-) polymerase protein cleavage; decreased Bcl-2 transcript and protein abundance; dephosphorylated the proapoptotic protein of the Bcl-2 family (BAD) at serine155; and depolarized mitochondria. FK506 (0.1 micromol/l) and another calcineurin inhibitor, deltamethrin (1 micromol/l), attenuated dexamethasone-induced cell death. |
2(0,0,0,2) | Details |