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Maccubbin D, Tipping D, Kuznetsova O, Hanlon WA, Bostom AG: Hypophosphatemic Effect of Niacin in Patients without Renal Failure: A Randomized Trial. Clin J Am Soc Nephrol. 2010 Mar 18.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a post hoc data analysis of serum phosphorus concentrations that had been determined serially (at baseline and weeks 4, 8, 12, 18, and 24) among 1547 patients who had dyslipidemia and were randomly assigned in a 3:2:1 ratio to treatment with extended release niacin (ERN; 1 g/d for 4 weeks and dose advanced to 2 g/d for 20 weeks) combined with the selective prostaglandin D2 receptor subtype 1 inhibitor laropiprant (L; n = 761), ERN alone (n = 518), or placebo (n = 268). |
31(0,1,1,1) |
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