Name | monoamine oxidase |
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Synonyms | Adrenalin oxidase; Amine oxidase; Amine oxidase [flavin containing] B; MAO B; MAOB; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type B… |
Name | sodium cyanide |
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CAS | sodium cyanide (Na(CN)) |
PubMed | Abstract | RScore(About this table) | |
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10092944 | Zajoncova L, Frebort I, Luhova L, Sebela M, Galuszka P, Pec P: Comparison of kinetic properties of amine oxidases from sainfoin and lentil and immunochemical characterization of /quinoprotein amine oxidases. Biochem Mol Biol Int. 1999 Jan;47(1):47-61. Both amine oxidases, like other plant Cu-amine oxidases, were inhibited by substrate analogs (1,5-diamino-3-pentanone, 1,4-diamino- and aminoguanidine), Cu2+ chelating agents (diethyltriamine, 1,10-phenanthroline, 8-hydroxyquinoline, 2,2'-bipyridyl, sodium cyanide and azide), some alkaloids (L-lobeline and cinchonine), some lathyrogens and aminoacetonitrile) and other inhibitors (benzamide oxime, oxime, and pargyline). |
33(0,1,1,3) | Details |
8117318 | Cassel GE, Persson SA, Stenstrom A: Effects of monoamine oxidase in striatal tissue from rat and pig. Biochem Pharmacol. 1994 Feb 9;47(3):499-504. In order to elucidate further these findings we examined the effects in vitro of sodium cyanide on rat and pig brain monoamine oxidase (MAO; EC 1.4.3.4). |
in vitro on the activity of 7(0,0,1,2) | Details |
3876442 | Peterson LA, Caldera PS, Trevor A, Chiba K, Castagnoli N Jr: Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). J Med Chem. 1985 Oct;28(10):1432-6. Results presented in this paper confirm the first assignment and establish that, although the proposed 6-cyano adduct is initially formed, the product that was isolated from the mitochondrial incubation mixtures of MPTP and sodium cyanide actually is the isomeric 2-cyano-1-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine. |
2(0,0,0,2) | Details |
1762989 | Abrahamsen J: Accumulation and release of modulation by of release from rabbit blood vessels in vitro. Pharmacol Toxicol. 1991;69 Suppl 3:1-40. Ouabain and iodoacetic acid, but not sodium cyanide and 2,4-dinitrophenol, reduced the accumulation of 3H derived from 3H-A. In all experiments, monoamine oxidase and catechol-O-methyltransferase were inhibited by treatment with pargyline and 3',4'-dihydroxy-2-methyl-propiophenone, respectively. |
and the 1(0,0,0,1) | Details |
2861994 | Chiba K, Peterson LA, Castagnoli KP, Trevor AJ, Castagnoli N Jr: Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Drug Metab Dispos. 1985 May-Jun;13(3):342-7. Detailed studies have been carried out on the monoamine oxidase B-catalyzed bioactivation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by rat brain mitochondrial preparations. Further characterization of MPDP+ was achieved by comparison of the diode array UV spectral tracings of the metabolite with synthetic MPDP+ perchlorate (CIO4-) and by the isolation of a cyano adduct from mitochondrial coincubation mixtures of MPTP and sodium cyanide. |
1(0,0,0,1) | Details |