Name | cholinesterase |
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Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
Name | piperonyl butoxide |
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CAS | 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole |
PubMed | Abstract | RScore(About this table) | |
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8658521 | Lessire F, Gustin P, Delaunois A, Bloden S, Nemmar A, Vargas M, Ansay M: Relationship between parathion and paraoxon toxicokinetics, lung metabolic activity, and cholinesterase inhibition in guinea pig and rabbit lungs. Toxicol Appl Pharmacol. 1996 Jun;138(2):201-10. After treatment with the cytochrome P450 inhibitor piperonyl butoxide, the above relations ceased to apply, but this treatment did not influence the kinetics of paraoxon and parathion uptake. |
5(0,0,0,5) | Details |
880389 | Eldefrawi AT, Mansour NA, Brattsten LB, Ahrens VD, Lisk DJ: Further toxicologic studies with commercial and candidate flame retardant chemicals. Bull Environ Contam Toxicol. 1977 Jun;17(6):720-6. A number of commercial and candidate flame retardants were studied with regard to their toxicity to goldfish, inhibition of cholinesterase, inhibition of acetyl binding to its receptor and insecticidal properties. Whereas several of the flame retardants showed little or no insecticidal properties when added alone to a housefly diet, piperonyl butoxide greatly synergised their toxicity to houseflies. |
2(0,0,0,2) | Details |
2894944 | Karara AH, Hayton WL: Metabolic inhibition and di-2-ethylhexyl pharmacokinetics in fish. Drug Metab Dispos. 1988 Jan-Feb;16(1):146-50. These effects may have been caused by the anticholinesterase activity of BNPP. To test this prediction, fish were treated with either piperonyl butoxide (PBO) or bis-(p-nitrophenyl) (BNPP) before and during their exposure to DEHP. |
1(0,0,0,1) | Details |
1139058 | Mirer FE, Cheever KL, Murphy SD: A comparison of gas chromatographic and anti-cholinesterase methods for measuring parathion metabolism in vitro. Bull Environ Contam Toxicol. 1975 Jun;13(6):745-50. |
1(0,0,0,1) | Details |
20021048 | Straus DL, Chambers JE: Effects of Piperonyl Butoxide on the Metabolism of DEF S,S,S-Tributyl Phosphorotrithioate) in Fingerling Channel Catfish. Toxicol Mech Methods. 2006;16(4):235-9. The present study was undertaken to investigate the significance of monooxygenases in bioactivation of DEF to a more effective anticholinesterase in fish. |
1(0,0,0,1) | Details |