Protein Information

Name acetylcholine receptor (protein family or complex)
Synonyms Acetylcholine receptor; Acetylcholine receptors

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
11561406 Nishiwaki H, Nakagawa Y, Ueno T, Kagabu S, Nishimura K: Insecticidal and binding activities of N3-substituted imidacloprid derivatives against the housefly Musca domestica and the alpha-bungarotoxin binding sites of nicotinic acetylcholine receptors. Pest Manag Sci. 2001 Sep;57(9):810-4.

The insecticidal test was conducted using the synergists piperonyl butoxide and propargyl propyl phenylphosphonate.
2(0,0,0,2) Details
11997976 Kagabu S, Nishiwaki H, Sato K, Hibi M, Yamaoka N, Nakagawa Y: Nicotinic acetylcholine receptor binding of imidacloprid-related diaza compounds with various ring sizes and their insecticidal activity against Musca domestica. Pest Manag Sci. 2002 May;58(5):483-90.

The insecticidal (in vivo) activity was evaluated against houseflies Musca domestica L under synergistic conditions with propargyl propyl phenyl phosphonate and piperonyl butoxide.
The binding activity of each compound to nicotinic acetylcholine receptor in vitro was measured using [125I] alpha-bungarotoxin.
1(0,0,0,1) Details
16470540 Miyagi S, Komaki I, Ozoe Y: Identification of a high-affinity binding site for dinotefuran in the nerve cord of the American cockroach. Pest Manag Sci. 2006 Apr;62(4):293-8.

The binding of the neonicotinoid insecticide dinotefuran to insect nicotinic acetylcholine receptors (nAChRs) was examined by a centrifugation method using the nerve cord membranes of American cockroaches and [3H] dinotefuran (78 Ci mmol-1).
A good correlation (r2=0.970) was observed between the -log IC50 values of the tested compounds and their piperonyl butoxide-synergised insecticidal activities (-log LD50 values) against German cockroaches.
1(0,0,0,1) Details