| 16491180 |
Moussa A, Coleman AW, Bencsik A, Leclere E, Perret F, Martin A, Perron H: Use of streptomycin for precipitation and detection of proteinase K resistant prion protein (PrPsc) in biological samples. Chem Commun. 2006 Mar 7;(9):973-5. Epub 2006 Jan 20.
The ability of streptomycin to form multimolecular aggregates with pathogenic prion proteins and their recovery by precipitation via a low-speed centrifugation step has been demonstrated; these novel properties of streptomycin make it a useful substance that increases the sensitivity of laboratory diagnostic techniques for prion infections in man and animals. |
12(0,0,2,2) |