| 16177391 |
Fukasawa Y, Kawamura I, Uchiyama R, Yamamoto K, Kaku T, Tominaga T, Nomura T, Ichiyama S, Ezaki T, Mitsuyama M: Streptomycin-dependent exhibition of cytokine-inducing activity in streptomycin-dependent Mycobacterium tuberculosis strain 18b. Infect Immun. 2005 Oct;73(10):7051-5.
Peritoneal exudate cells of mice were stimulated with a streptomycin-dependent Mycobacterium tuberculosis strain, 18b. Gamma interferon production by natural killer cells depending on interleukin-12 and interleukin-18 was induced only in the presence of a high dose of streptomycin. This study suggested the requirement of active bacterial metabolism for this host response. |
31(0,1,1,1) |