Protein Information

ID 183
Name intestinal alkaline phosphatase
Synonyms ALPI; IAP; Intestinal alkaline phosphatase; Intestinal alkaline phosphatase precursor; Intestinal alkaline phosphatases; Intestinal alkaline phosphatase precursors

Compound Information

ID 222
Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference

PubMed Abstract RScore(About this table)
7112611 Saigal S, Bhatnagar VK, Malviya AN: Effect of selected pesticides on alkaline and acid phosphatase in the rat. Toxicol Lett. 1982 Jul;12(2-3):177-80.
A single oral dose of DDT (60.0 mg/kg), malathion (687.5 mg/kg), phosalone (60.0 mg/kg) and elsan (175.0 mg/kg) to adult male albino rats produced significant impairment in acid and alkaline phosphatase activities within 1 h of dosing. Renal and hepatic alkaline phosphatase activity was significantly inhibited in all cases, while treatment with malathion and phosalone resulted in an increase in intestinal alkaline phosphatase activity. Elsan induced an increase in acid phosphatase activity in liver, kidney and intestine whereas the response to DDT, malathion and phosalone was variable.
31(0,1,1,1)