| ID | 20 |
|---|---|
| Name | isocitrate dehydrogenase |
| Synonyms | ICD M; IDH; IDP; NADP(+) specific ICDH; Oxalosuccinate decarboxylase; IDH 2; IDH2; IDHM… |
| ID | 183 |
|---|---|
| Name | lindane |
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 1723596 | Philip GH, Reddy PM, Ramamurthi R: Changes in the carbohydrate metabolism in the selected tissues of Mus booduga gray after BHC treatment. Biochem Int. 1991 Aug;24(6):1165-71. Adult mice, Mus booduga were fed orally with bennzenehexachloride (BHC) at a dose of 50 mg/kg body weight every day for 1, 5 and 15 days. Significant decrease in the content was observed at all periods of treatment. In support of this increase in lactate content and lactate dehydrogenase (LDH) activity was noticed in all the three tissues. Enzymes of TCA cycle namely isocitrate dehydrogenase (ICDH), succinate dehydrogenase (SDH) and malate dehydrogenase (MDH) were inhibited suggesting abnormality in mitochondrial oxidative metabolism as a consequence of BHC toxicity. |
1(0,0,0,1) |