Protein Information

ID 88
Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

ID 222
Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference

PubMed Abstract RScore(About this table)
6701915 Ansari BA, Kumar K: Malathion toxicity: in vivo inhibition of acetylcholinesterase in the fish Brachydanio rerio (Cyprinidae). Toxicol Lett. 1984 Mar;20(3):283-7.
Acetylcholinesterase (AChE) activity in the nervous tissue (brain) of the fish Brachydanio rerio was significantly inhibited by exposure to the organophosphorus (OP) pesticide, malathion. The inhibition was dose- as well as time-dependent. The fish survived even when the activity of the enzyme was inhibited by 90%. There was a significant recovery in the activity of AChE when malathion stress was lifted.
118(1,2,3,3)