Protein Information

ID 88
Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

ID 222
Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference

PubMed Abstract RScore(About this table)
6364457 Sahib IK, Prasada Rao KS, Sambasiva Rao KR, Ramana Rao KV: Sublethal toxicity of malathion on the proteases and free amino acid composition in the liver of the teleost, Tilapia mossambica (Peters). Toxicol Lett. 1984 Jan;20(1):59-62.
Exposure of fish to a sublethal concentration of malathion showed a significant inhibition of acetylcholinesterase (AChE) activity. The levels of protease were markedly elevated with a consequent increase in most of the free amino acids. However, the levels of glutamic acid and valine, phenylalanine and methionine complex remained unchanged, while aspartic acid showed a marked drop. These changes are discussed in relation to the sublethal stress induced by malathion.
81(1,1,1,1)