| 3741958 |
Deng XM, Castillo EJ, Anderson JM: Surface modification of soft contact lenses: silanization, wettability and lysozyme adsorption studies. Biomaterials. 1986 Jul;7(4):247-51.
The surface reactions of poly (2-hydroxyethylmethacrylate) (PHEMA) and the copolymer poly (HEMA-methacrylic acid) (PHEMA/MAA) with methyltrimethoxysilane, ethyltrimethoxysilane and phenyltrimethoxysilane have been characterized by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. A model compound, hydroxyethyl isobutyrate was synthesized and subsequently reacted with phenyltrimethoxysilane. Its FTIR spectrum was compared with the ATR-FTIR spectra mentioned above. Protein adsorption experiments showed that silanized PHEMA/MAA soft contact lenses adsorbed less lysozyme than the untreated lenses. |
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