Protein Information

ID 36
Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

ID 222
Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference

PubMed Abstract RScore(About this table)
7927578 Mourya DT, Gokhale MD, Mishra AC: Biochemical basis of DDT-resistance in Aedes aegypti population from a dengue affected area in Shahjahanpur city. Indian J Med Res. 1994 May;99:212-5.
Entomological studies conducted in Jalalnagar, Shahjahanpur city, Uttar Pradesh, India, during an outbreak of dengue in 1992, showed that Ae. aegypti mosquitoes were resistant to DDT and had some tolerance to malathion in the adults and the larvae. Biochemical analysis suggested that DDT resistance was related to elevated glutathione s-transferase and tolerance to malathion was due to a little increase in esterase activity. Crosses of DDT-resistant and susceptible strain suggested that resistance was codominant (metabolic type).
6(0,0,1,1)