| 1354835 |
Sergieva VP, Gracheva GV: [Age-related changes in mosquito insecticide resistance and their relation to the mechanisms of detoxication]. Med Parazitol. 1992 Jan-Feb;(1):11-5.
The mechanisms of DDT, permethrin and malathion resistance were determined indirectly by means of synergists inhibiting the detoxification enzymes. It was found that metabolic resistance dependent on glutathione-S-transferase, MFO and carboxylesterase is the most liable to age changes. Such changes are less expressive in mosquitos which have supposedly kdr-resistance. In young mosquitos (1-2 days) of all species, the rate of synergism is relatively low and fails to explain high resistance which is usual for juvenile specimen. |
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