| 2047580 |
Udom CE, Smith TJ: Hypolipidemic effect of metrifonate and the relationship to serum cholinesterase inhibition. Res Commun Chem Pathol Pharmacol. 1991 Mar;71(3):387-90.
The organophosphate metrifonate has been demonstrated to produce a hypolipidemic effect in the Syrian golden hamster as demonstrated by turbidimetric analysis of lipoprotein precipitation by heparin. A sex-related difference in sensitivity to the hypolipidemia may exist, although metrifonate appears to be an effective serum cholinesterase inhibitor in both sexes. Therefore, metrifonate may be a useful probe in the investigation of organophosphate-induced hypolipidemia. |
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