Protein Information

ID 1206
Name Lactoferrin
Synonyms GIG12; Growth inhibiting protein 12; HLF 2; HLF2; LF; LTF; Lactoferrin; Lactotransferrin…

Compound Information

ID 965
Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference

PubMed Abstract RScore(About this table)
6469273 Amouric M, Marvaldi J, Pichon J, Bellot F, Figarella C: Effect of lactoferrin on the growth of a human colon adenocarcinoma cell line--comparison with transferrin. In Vitro. 1984 Jul;20(7):543-8.
Lactoferrin was examined for its effect on the growth of a human colon adenocarcinoma cell line (HT 29) in culture and its action was compared to that produced by transferrin and two different iron solutions (ferrous sulfate and ferric chloride). When transferrin was replaced by either iron solutions the cell grew in proportion to the quantity added and the maximal effect obtained was identical to that produced by transferrin alone. When transferrin was replaced by lactoferrin the cells were unable to proliferate for a long time. However, in the presence of low-concentration iron solutions, lactoferrin stimulated the cell growth, and the effect was more pronounced with the ferric chloride solution.
9(0,0,1,4)