Protein Information

ID 688
Name NADH dehydrogenase
Synonyms B14.5b; NADH dehydrogenase; CI B14.5b; Complex I B14.5b; HLC 2; HLC2; NADH dehydrogenase [ubiquinone] 1 subunit C2; NADH ubiquinone oxidoreductase subunit B14.5b…

Compound Information

ID 1341
Name rotenone
CAS

Reference

PubMed Abstract RScore(About this table)
1239310 Yaguzhinski LS, Kolesova GM: [Model of bifunctional binding of rotenone and piericidin with mitochondrial NADH-dehydrogenase]. Biokhimiia. 1975 May-Jun;40(3):456-60.
Based on authors' and literature data on the effect of inhibitors of mitochondrial NADH-dehydrogenase a scheme concerning bifunctional binding of specific inhibitors--piericidin A and rotenone with the enzyme is suggested. Analysis on the models, made in correspondence with the requirements of this scheme, permitted to propose conformations in which rotenoides interact with the enzyme.
162(2,2,2,2)