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Popov VN: Possible role of free oxidation processes in the regulation of reactive oxygen species production in plant mitochondria. Biochem Soc Trans. 2003 Dec;31(Pt 6):1316-7. The non-coupled substrate oxidation mediated by components of the electron transport chain that are not coupled to energy accumulation (such as plant alternative oxidase and rotenone-insensitive NADH dehydrogenases) and uncoupled respiration are peculiar features of plant mitochondria. The physiological significance of such energy-wasting oxidation processes is still debated. It is proposed that non-coupled oxidation could regulate the level of reduction of components of the electron transport chain and the rate of one-electron reduction of oxygen, thereby affecting the rate of formation of reactive oxygen species. |
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