| 6713004 |
Liberman EA, Tsofina LM: [Effect of phosphodiesterase inhibitors on the membrane potential and respiration of mitochondria]. Biofizika. 1984 Jan-Feb;29(1):158-9.
Effect of papaverine, 3-isobutyl-1-methylxanthine and SQ-20009 was studied. It was shown that papaverine (50 microM) had rotenone--like action on isolated rat liver mitochondria decreasing their membrane potential and blocking respiration upon beta-oxybutyrate oxidation. Papaverine did not practically influence the membrane potential and oxygen consumption upon succinate oxidation. SQ-20009 effect was much less than that of papaverine. 3-isobutyl-1-methylxanthine (50-200 microM) was uneffective at all. |
1(0,0,0,1) |