| 2502429 |
Jacobs JM, Sinclair PR, Lambrecht RW, Sinclair JF: Effects of iron-EDTA on uroporphyrinogen oxidation by liver microsomes. . FEBS Lett. 1989 Jul 3;250(2):349-52.
Uroporphyrinogen oxidation by hepatic microsomes from chick embryos or mice pretreated with methylcholanthrene was increased by addition of iron-EDTA. This increase was partially prevented by catalase, mannitol, ketoconazole and piperonyl butoxide, whereas only ketoconazole and piperonyl butoxide inhibited the oxidation in the presence and absence of iron-EDTA. These data suggest that the oxidations of uroporphyrinogen in the presence and absence of added iron occur by different mechanisms. |
31(0,1,1,1) |