Protein Information

ID 95
Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

ID 186
Name dichlorvos
CAS 2,2-dichloroethenyl dimethyl phosphate

Reference

PubMed Abstract RScore(About this table)
7344402 Slomka MB, Hine CH: Clinical pharmacology of dichlorvos. . Acta Pharmacol Toxicol. 1981;49 Suppl 5:105-8.
Polyvinyl resin formulation pellets (V-3 and V-12) containing dichlorvos were administered to male volunteers in single doses up to 32 mg/kg and repeated doses up to 16 mg/kg/day for up to three weeks. The cholinesterase activity depressions following single doses were dose related. Following multiple doses, the plasma cholinesterase activity was maximally depressed at all dose levels and the RBC cholinesterase activity depression was dose related.
2(0,0,0,2)