| 10631757 |
Pandeya SN, Ponnilavarasan I, Pandey A, Lakhan R, Stables JP: Evaluation of p-nitrophenyl substituted semicarbazones for anticonvulsant properties. Eur J Neurosci. 1994 Aug 1;6(8):1275-80.
A series of p-nitrophenyl substituted semicarbazones has been synthesised and their anticonvulsant activity was screened against MES, scPTZ and scSTY. 4 (4'-Nitrophenyl)-o-nitrobenzaldehyde semicarbazone has been found to be the most active in all these tests. The studies revealed that a primary amino function is not essential for anticonvulsant activity in the semicarbazone series of compounds. Presumably these compounds could further act on glycine receptors. |
1(0,0,0,1) |