Protein Information

ID 65
Name NMDA receptor (protein family or complex)
Synonyms Glutamate [NMDA] receptor; Glutamate [NMDA] receptors; N methyl D aspartate receptor; N methyl D aspartate receptors; NMDA receptor; NMDA receptors

Compound Information

ID 336
Name strychnine
CAS strychnidin-10-one

Reference

PubMed Abstract RScore(About this table)
9459010 Micheli F, Cugola A, Donati D, Missio A, Pecunioso A, Reggiani A, Tarzia G: 2,3-Dihydro-6,7-dichloro-pyrido [2,3-b] pyrazine-8-oxide as selective glycine antagonist with in vivo activity. Bioorg Med Chem. 1997 Dec;5(12):2129-32.
2,3-Dihydro-6,7-dichloro-pyrido [2,3-b] pyrazine-8-oxide was synthesized and evaluated for in vitro/in vivo antagonistic activity at the strychnine insensitive glycine binding site on the NMDA receptor revealing it to be a useful tool to evaluate the effectiveness of glycine antagonists in vivo.		 81(1,1,1,1)