Protein Information

ID 88
Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

ID 186
Name dichlorvos
CAS 2,2-dichloroethenyl dimethyl phosphate

Reference

PubMed Abstract RScore(About this table)
9504975 Tripathi AM, Agarwal RA: Molluscicidal and anti-AChE activity of tertiary mixtures of pesticides . Arch Environ Contam Toxicol. 1998 Apr;34(3):271-4.
We studied the toxicity and in vivo inhibition of acetylcholinesterase (AChE) by the organophosphate Nuvan (dichlorvos); Nuvan mixed with a mixed function oxidase inhibitor, piperonyl butoxide (PB); Nuvan with a pyrethroid Decis (deltamethrin); and a tertiary mixture of Nuvan, PB, and Decis in the snail Lymnaea acuminata. Nuvan was highly toxic to the snail and was a strong inhibitor of AChE activity. Both PB and Decis act synergistically with Nuvan when given together in a 1:5 and 1:46 ratio, respectively. When a tertiary mixture of Nuvan, Decis, and PB was given in a 1:46:5 ratio, the toxicity of the mixture was higher in comparision to the binary mixture of Nuvan + PB or Nuvan + Decis.
83(1,1,1,3)