ID | 450 |
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Name | demethylase |
Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
ID | 182 |
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Name | endosulfan |
CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
PubMed | Abstract | RScore(About this table) |
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4093546 | Tyagi SR, Sriram K, Narayan S, Misra UK: Induction of cytochrome P-450 and synthesis by endosulfan in liver of rats: effect of quality of dietary proteins. J Environ Sci Health B. 1985 Dec;20(6):651-64. Administration of endosulfan significantly increased microsomal protein, cytochrome P-450 content and the activity of aminopyrine N-demethylase. Effect of endosulfan and actinomycin D either alone or together on microsomal protein, cytochrome P-450, cytochrome c reductase, hydroxylase, aminopyrine N-demethylase, content, incorporation of 3H- and 14C- were studied in rats given amino acid deficient and supplemented diets. Administration of endosulfan significantly increased the above parameters in both the dietary groups, whereas administration of actinomycin D did not have any effect in rats fed supplemented diets, however, significant decrease in the PC and the incorporation of and into PC of rats fed deficient diet were observed. A positive correlation in the effect of endosulfan on hepatic mixed function oxidase activity and hepatic is observed. |
12(0,0,2,2) |