multidrug resistance protein 1

General Information (Source: NCBI Gene,UniProt)

Text mining Term multidrug resistance protein 1
UniProt ID Q8R427_RAT
Name ATP-binding cassette protein B1b
Gene Names Abcb1b
Synonyms:Abcb1
Taxonomy Rattus norvegicus

General annotation

Function
Subcellular location

Gene Ontology

GO:0042626 ATPase activity, coupled to transmembrane movement of substances MF
GO:0005524 ATP binding MF
GO:0016021 integral to membrane CC

Sequence

>gi|25453370|ref|NP_036755.2| multidrug resistance protein 1 [Rattus norvegicus]
MEFEEGLNGTADKNFSKMGKKSKKEKEKKPAVGIFGMFRYADWLDKLCMALGTLAAIIHGTLLPLLMLVF
GYMTDSFTQAETRILPSVTNQSEINSTQTVSDSSLEEDMAMYAYYYTGIGAGVLIVAYIQVSLWCLAAGR
QIHKIRQKFFHAIMNQEIGWFDVNDAGELNTRLTDDVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGW
KLTLVILAVSPLIGLSSAMWAKVLTSFTNKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLE
EAKRVGIKKAITANISIGIAYLLVYASYALAFWYGTSLVLSNEYSIGQVLTVFFSILLGTFSIGHLAPNI
EAFANARGAAYEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEFKNVYFNYPSRSEVKILKGLNLKVKSGQT
VALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGR
ENVTMDEIEKAVKEANAYDFIMKLPHKFNTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALD
TESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKGIYFKLVMTQTRG
NEIEPGNNAYESQSDTGASELTSEKSKSPLIRRSIRRSIHRRQDQERRLSSKEDVDEDVPMVSFWQILKL
NISEWPYLVVGVLCAVINGCIQPVFAIVFSKIVGVFSRDDDHETKQRNCNLFSLLFLVMGMISFVTYFFQ
GFAFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRLASDASNVKGAMGSRLAVVTQNVANL
GTGIILSLVYGWQLTLLLVVIIPLIVLGGIIEMKLLSGQALKDKKELEISGKIATEAIENFRTVVSLTRE
QKFETMYAQSLQIPYRNALKKAHVFGITFAFTQAMIYFSYAACFRFGAYLVARELMTFENVMLVFSAVVF
GAMAAGNTSSFAPDYAKAKVSASHIIRIIEKIPEIDSYSTEGLKPNWLEGNVKFNGVMFNYPTRPNIPVL
QGLSFEVKKGQTLALVGSSGCGKSTVVQLLERFYNPMAGTVFLDGKEIKQLNVQWLRAHLGIVSQEPILF
DCSITENIAYGDNSRVVSHEEIVRAAREANIHQFIDSLPEKYNTRVGDKGTQLSGGQKQRIAIARALVRQ
PHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQ
KGIYFSMVQAGAKRS

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.144554
PDB
RefSeq NP_036755.2
Pfam PF00005
PF00664