cholinesterases

General Information (Source: NCBI Gene,UniProt)

Text mining Term cholinesterases
UniProt ID ACES_LEPDE
Name AChE
Acetylcholinesterase
Gene Names
Taxonomy Leptinotarsa decemlineata

General annotation

Function Rapidly hydrolyzes choline released into the synapse.
Subcellular location Cell junction, synapse (By similarity). Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Note=Attached to the membrane of the neuronal cholinergic synapses by a GPI- anchor (By similarity).

Gene Ontology

GO:0030054 cell junction CC
GO:0001507 acetylcholine catabolic process in synaptic cleft BP
GO:0004091 carboxylesterase activity MF
GO:0003990 acetylcholinesterase activity MF
GO:0005886 plasma membrane CC
GO:0031225 anchored to membrane CC

Sequence

>gi|2494392|sp|Q27677.1|ACES_LEPDE RecName: Full=Acetylcholinesterase; Short=AChE; Flags: Precursor
MGQLSILCLFVTVCASVCGYSWPSDETTTKPSQFKDFHTDPLVVETTSGLVRGYSKTVLGREVHVFTGIP
FAKPPIEQLRFKKPVPIDPWHGILDATKQPNSCFQERYEYFPGFEGEEMWNPNTNISEDCLYLNIWVPQR
LRIRHHADKPTIDRPKVPVLIWIYGGGYMSGTATLDVYDADIIAATSDVIVASMQYRLGSFGFLYLNRYF
PRGSDETPGNMGLWDQILAIRWIKDNAAAFGGDPDLITLFGESAGGGSISIHLISPVTKGLVRRGIMQSG
TMNAPWSYMSGERAEQIGKILIQDCGCNVSLLENSPRKVMDCMRAVDAKTISLQQWNSYSGILGFPSTPT
IEGVLLPKHPMDMLAEGDYEDMEILLGSNHDEGTYFLLYDFIDFFEKDGPSFLQREKYHDIIDTIFKNMS
RLERDAIVFQYTNWEHVHDGYLNQKMIGDVVGDYFFVCPTNNFAEVAADRGMKVFYYYFTHRTSTSLWGE
WMGVIHGDEVEYVFGHPLNMSLQFNSRERELSLKIMQAFARFATTGKPVTDDVNWPLYTKDQPQYFIFNA
DKNGIGKGPRATACAFWNDFLPKLRDNSGSEEAPCVNTYLSKIRSSSNELLPPSTSLVLIWIMTLLNAL

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00135