GABA receptor (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term GABA receptor (protein family or complex)
UniProt ID GBRB_DROME
Name Protein cyclodiene resistance
Gamma-aminobutyric acid receptor subunit beta
GABA(A) receptor subunit beta
Gene Names Rdl
Taxonomy Drosophila melanogaster

General annotation

Function GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel.
Subcellular location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0030431 sleep BP
GO:0030054 cell junction CC
GO:0030594 neurotransmitter receptor activity MF
GO:0009612 response to mechanical stimulus BP
GO:0034707 chloride channel complex CC
GO:0005886 plasma membrane CC
GO:0005230 extracellular ligand-gated ion channel activity MF
GO:0030425 dendrite CC
GO:0042749 regulation of circadian sleep/wake cycle BP
GO:0045211 postsynaptic membrane CC
GO:0050805 negative regulation of synaptic transmission BP
GO:0005254 chloride channel activity MF
GO:0090328 regulation of olfactory learning BP
GO:0030424 axon CC
GO:0004890 GABA-A receptor activity MF

Sequence

>gi|405123|gb|AAA19249.1| GABA receptor [Drosophila melanogaster]
MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGNKRIHTVQAATGGGSMLGDVNISAILDSFSISY
DKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYGKRPGVETLSVGSEFIKNI
WVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTM
RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL
IVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYAT
VGYMAKRIQVRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVG
MGMGPEHRHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKG
GTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKDINKLLG
ITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEE

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dm.2698
PDB
RefSeq NP_729462.1
NP_729461.1
NP_523991.2
Pfam PF02931
PF02932