gamma aminobutyric acid receptor (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term gamma aminobutyric acid receptor (protein family or complex)
UniProt ID GBRB_DROSI
Name GABA(A) receptor
Protein cyclodiene resistance
Gamma-aminobutyric acid receptor subunit beta
Gene Names Rdl
Taxonomy Drosophila simulans

General annotation

Function GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel.
Subcellular location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0030594 neurotransmitter receptor activity MF
GO:0004890 GABA-A receptor activity MF
GO:0005230 extracellular ligand-gated ion channel activity MF
GO:0005254 chloride channel activity MF
GO:0005886 plasma membrane CC
GO:0034707 chloride channel complex CC
GO:0045211 postsynaptic membrane CC
GO:0030054 cell junction CC

Sequence

>gi|44887891|sp|Q9BLY8.1|GBRB_DROSI RecName: Full=Gamma-aminobutyric acid receptor subunit beta; AltName: Full=GABA(A) receptor; AltName: Full=Protein cyclodiene resistance; Flags: Precursor
MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSY
DKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNI
WVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTM
RDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL
IVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYAT
VGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVG
MGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKG
GTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKDINKLLG
ITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEE

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF02931
PF02932