MDM2

General Information (Source: NCBI Gene,UniProt)

Text mining Term MDM2
UniProt ID UBP7_DROME
Name Deubiquitinating enzyme 7
Ubiquitin-specific-processing protease 7
Ubiquitin thiolesterase 7
Ubiquitin carboxyl-terminal hydrolase 7
Gene Names Usp7
Taxonomy Drosophila melanogaster

General annotation

Function Cleaves ubiquitin fusion protein substrates (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0043234 protein complex CC
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0035328 transcriptionally silent chromatin CC
GO:0016578 histone deubiquitination BP
GO:0005634 nucleus CC
GO:0004843 ubiquitin-specific protease activity MF
GO:0006342 chromatin silencing BP
GO:0004221 ubiquitin thiolesterase activity MF
GO:0005700 polytene chromosome CC

Sequence

>gi|74871727|sp|Q9VYQ8.1|UBP7_DROME RecName: Full=Ubiquitin carboxyl-terminal hydrolase 7; AltName: Full=Ubiquitin thiolesterase 7; AltName: Full=Ubiquitin-specific-processing protease 7; Short=Deubiquitinating enzyme 7
MEIETDQSIEAMDTQDTQEVEILTSDLQQTQQQRNSPPQLPKFKNLIQPQLHAVGAVTQLPSENGNMPPQ
QLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVRMLPWRIMVIPNDRA
LGFFLQCNGENDSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKSY
VHNNSITLEVHVVADAPHGVLWDSKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSS
KSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGL
FEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEASKGV
IFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLAESENTLADYVLHAVLVHSGDNHGGH
YVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDEISFHAKCSNAYMLVYIRQSELDRVLGDITE
SEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLEKVHPRVFRIKQNQTVD
ELVDLFVRGFGVSRQRMRMWNLCTAQTQKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGPLPP
FNPKTESLLFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNE
PIESALFIPQDHLQGHILIFERENVDAKLDLPTVGDYFLDLVYRIEIIFSDKCNPNEPDFTLELSNRYNY
DQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSIHEL
DNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKDDI
PLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQLAENEFLIPVAHFSKELYNSFGIPFLTKARQGEPYGA
LKQRIQRRLNVQDKEWENYKFCVISMGHNADVNDNTPVDLEVYRSWTSGQLPFFGLDHINKSRKRSSLNF
SEKAIKIYN

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dm.3592
PDB
RefSeq NP_572779.2
Pfam PF00917
PF00443
PF12436