| Text mining Term | cytokine receptor (protein family or complex) |
|---|---|
| UniProt ID | DOME_DROME |
| Name |
Cytokine receptor Protein domeless |
| Gene Names |
dome
|
| Taxonomy | Drosophila melanogaster |
| Function |
Critical for epithelial morphogenesis during oogenesis; border cell migration. Required in the germarium for the polarization of follicle cells during encapsulation of germline cells. Required for embryonic segmentation and trachea specification. Essential receptor molecule for upd and JAK/STAT signaling during oogenesis. |
|---|---|
| Subcellular location |
Apicolateral cell membrane; Single-pass type I membrane protein. Note=Apicolateral membranes in follical cells. |
| GO:0007616 | long-term memory | BP |
| GO:0004725 | protein tyrosine phosphatase activity | MF |
| GO:0004888 | transmembrane signaling receptor activity | MF |
| GO:0007442 | hindgut morphogenesis | BP |
| GO:0007350 | blastoderm segmentation | BP |
| GO:0001745 | compound eye morphogenesis | BP |
| GO:0016324 | apical plasma membrane | CC |
| GO:0007298 | border follicle cell migration | BP |
| GO:0007259 | JAK-STAT cascade | BP |
| GO:0008284 | positive regulation of cell proliferation | BP |
| GO:0016021 | integral to membrane | CC |
| GO:0006955 | immune response | BP |
| GO:0007425 | epithelial cell fate determination, open tracheal system | BP |
| GO:0016327 | apicolateral plasma membrane | CC |
>gi|17367176|sp|Q9VWE0.1|DOME_DROME RecName: Full=Cytokine receptor; AltName: Full=Protein domeless; Flags: Precursor MVAQEQLVLLLMLLAGCRGGANAILDPGWVIPSKVEQLIGGDFNLSCTLNEDYFNGKSAEDCPVEKLYFT GGGRVYRDSKHIRILNNTTILFSDTNAVEQENDYHCMCDEYVINKSKVYVGTRPLLVRDFNCLDYDFQFM VCNFTQPPNTVITKYNISYNTNNDWRYSNTLDCNFDSAPVVTCNLTDDNYKRFSETFYFRLSISNALGHE TQPITINHFERLVPARPGQNLTLLNRTESSVCLSWEMPRRSNYNRGLVWQVRVTPQNFEPITRPSWRNHT LTIKDTLCLTELPFAGYNYTLRVRVRANQNNTLWSEPMIYAFATAPAPPRRPPRVTYGSFYVYSSEKAMR FYWEPLEEHELNGPDFRYSISEYRINGTAVDPGLIKVESNSAMIDHWSMSAVHHFLIRSSNSQGLSVNAT PMTIGPISNRDFKVREPRNIRSVYHPTNKSYTLSWDPPSDQRELQNYTVFWCVPKPGLQSECEGSIRFAE VASGLHHFTTSPDQLLTLHMAVSANYQSHNTGLHWAICSSDKKDDLAKMEPSIDVATSTSLTVSWSERVC AVILAGYNLTYCQRSAGRPDNCTTVTIDRYTNKHVIQNLVPYTDYSVKMLMYSDSRVSKYSDELVNRTGE AAPSQPRELQLIRVTSDSVELAWKPPLLANGVVRAYEGTFRSLHDNVTDTFRVSASADELVNNEKPITYR LGNLTAFTKYEISVRARTVYPSEPSNVILFSTAIGVPSPPQLYVINNPDQSSRLDWEPPRTPAGRIDFYE ISLRDNNASCLTSTILPGRNLSYVMATPRCTSHNPFQLAVRAINVEQHPQLNGADAAEGAVLLMSTNGKG CEARTDALGEEERLQFEAYAANMTAYRLYRSDWGIYGFICTPDTHSVKAMYQTIEVTVAILVLGVIFYLV YKKYRKMSDIGLVLPQGIMETMKKPIDMGGLGLGLGPDSSVSGGIVCTRVDDSPPYTPQDLPHDFSSCGS ESSKLLLRTASSSGGGGCVDRDGYDDNHETGPISAVGPPTSYLAMRHGLLVQNDRERERERDREQERERE QQQQQRESEMDREQSCTNGYIKPTQMKSWGGNGPSDNDHTFSVPSTAMTAPMSQPLSQIPLSGYVPVPIP QSRFNPAPVQPFGSPAVPSAATAAAASTFFPPAHLLNMDNYVQASDLHKLKPLVAAPLSQTGGPAFAGSS PATSPPLQLPPVHAASPAAATPKMADIGYTTMEQLQLTGLIKPPLAATVGSPTHAAGGAPGGGNQHSRLQ PQINGYVTPQDLNAMAHNRHVL |
| Ensembl Gene | |
|---|---|
| UniGene |
Dm.2836 |
| PDB | |
| RefSeq |
NP_523412.1 |
| Pfam |
PF00041 |