temephos

Identification (Source:EPA,EU)

ID 1559
Name temephos
CAS 3383-96-8
IUPAC
Inchi InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3
CIPAC 340
EPA Code 059001
Formula C16H20O6P2S3
SMILES S=P(OC)(OC)Oc2ccc(Sc1ccc(OP(=S)(OC)OC)cc1)cc2
Status Not Approved

Classification

Mode of Action Non-systemic. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide, Veterinary treatment
Chemical Group Organophosphate
Classification organothiophosphate insecticides
phenyl organothiophosphate insecticides

Properties (Source:PubChem)

Molecular Weight 466.47
Physical State Colourless crystals
AlogP 4.91
H-Bond Donor 0
H-Bond Acceptor 9
Surface Area 421.12
Polar Surface Area 164.48

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 1.4 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.00001 mg l-1
Birds Acute LD50 1200 mg kg-1
Fish Acute 96 hour LC50 3.49 mg l-1
Honeybees Acute 48 hour LD50 1.55 μg bee-1
Mammals Acute oral LD50 4204 mg kg-1
Mammals Short term dietary NOEL 300 ppm diet
Bio-concentration factor BCF 2300
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
P glycoprotein 122(1,2,3,7) Details
Salvador 89(1,1,2,4) Details
esterase A4 81(1,1,1,1) Details
Acetylcholinesterases 85(0,0,11,30) Details
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