| Name | ATPase |
|---|---|
| Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
| Name | anthraquinone |
|---|---|
| CAS | 9,10-anthracenedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6320499 | Kawai K, Kato T, Mori H, Kitamura J, Nozawa Y: A comparative study on cytotoxicities and biochemical properties of anthraquinone mycotoxins emodin and skyrin from Penicillium islandicum Sopp. Toxicol Lett. 1984 Feb;20(2):155-60. The anthraquinone mycotoxins emodin and skyrin were examined for the inhibitory effects on murine leukemia L1210 culture cells, oxidative phosphorylation of rat liver mitochondria, and Na+, K+-activated ATPase activity of rat brain microsomes to find the differences between their modes of toxic action. |
81(1,1,1,1) | Details |
| 17356235 | Breier A, Bohacova V, Docolomansky P: Inhibition of (Na (+)/K (+))-ATPase by Cibacron Blue 3G-A and its analogues. Gen Physiol Biophys. 2006 Dec;25(4):439-53. A specific feature of anthraquinone dyes (AD) is to mimic the nucleotides ATP, ADP, NAD and enabling them to act as ligands in interaction with nucleotide-binding sites of several enzymes and receptors. |
7(0,0,0,7) | Details |
| 11316513 | Zucchi R, Ronca F, Ronca-Testoni S: Modulation of sarcoplasmic reticulum function: a new strategy in cardioprotection?. Pharmacol Ther. 2001 Jan;89(1):47-65. This thesis is supported by the review of experimental studies in which modulators of the SR Ca (2+)-ATPase or SR Ca (2+) release channel (ryanodine receptor) have been used. In addition, the role of the SR in ischemic preconditioning and in some instances of toxic myocardial injury (particularly, anthraquinone-induced injury) is discussed. |
1(0,0,0,1) | Details |
| 16386736 | Zhang HL, Tang ZY, Yang JX, Zhang Y, Li Y, Lin Y: Bi-directional regulation of emodin and on smooth muscle myosin of gizzard. FEBS Lett. 2006 Jan 23;580(2):469-73. Epub 2005 Dec 22. This study is to reveal the characteristics of bidirectional regulation of emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) and on gizzard smooth muscle myosin. Our results indicate that: (a) emodin demonstrates stimulatory effects, and produces inhibitory effects on myosin phosphorylation and Mg (2+)-ATPase activities of Ca (2+)/calmodulin-dependent phosphorylated myosin in a dose-dependent manner; (b) a combination of emodin and enhances phosphorylation and Mg (2+)-ATPase activities for partially phosphorylated myosin and inhibits those activities for fully phosphorylated myosin; (c) 1-(5-Chloronaphthalene-1-sulfonyl)-1H2-hexahydro-1,4-diazepine inhibits myosin phosphorylation in the presence of emodin and/or |
1(0,0,0,1) | Details |
| 2835785 | Wanitschke R, Karbach U: Influence of rhein on rat colonic Na+,K+-ATPase and permeability in vitro. Pharmacology. 1988;36 Suppl 1:98-103. Rhein, an aglucone of a laxative-acting anthraquinone, which induces net secretion in the human jejunum and colon, does not induce net secretion under open circuit current in in vitro conditions but reduces net absorption of electrolytes and water. |
1(0,0,0,1) | Details |
| 10991929 | Zucchi R, Yu G, Ghelardoni S, Ronca F, Ronca-Testoni S: Effect of MEN 10755, a new disaccharide analogue of doxorubicin, on sarcoplasmic reticulum Ca (2+) handling and contractile function in rat heart. Br J Pharmacol. 2000 Sep;131(2):342-8. The use of anthraquinone antineoplastic agents is limited by their cardiac toxicity, which is largely due to activation of the sarcoplasmic reticulum (SR) Ca (2+) release channel (ryanodine receptor). |
0(0,0,0,0) | Details |