lambda-cyhalothrin

Identification (Source:EPA,EU)

ID 1605
Name lambda-cyhalothrin
CAS 91465-08-6
IUPAC
Inchi InChI=1S/2C23H19ClF3NO3/c2*1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h2*3-12,17-18,20H,1-2H3/b2*19-12-/t2*17-,18+,20-/m10/s1
CIPAC 463
EPA Code
Formula C23H19ClF3NO3
SMILES Cl\C(=C/[C@H]3[C@@H](C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C)C(F)(F)F
Status Approved

Classification

Mode of Action Non-systemic, contact and stomach action. Some repellant properties. Sodium channel modulator.
Pesticide Type Insecticide
Chemical Group Pyrethroid
Classification pyrethroid ester insecticides

Properties (Source:PubChem)

Molecular Weight 449.85
Physical State Colourless solid
AlogP 5.791
H-Bond Donor 0
H-Bond Acceptor 4
Surface Area 408.48
Polar Surface Area 59.32

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Chronic 96 hour NOEC, growth > 0.31 mg l-1
Algae Acute 72 hour EC50, growth > 0.3 mg l-1
Aquatic crustaceans Acute 96 hour LC50 0.000003 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.3 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.00036 mg l-1
Birds Acute LD50 > 3950 mg kg-1
Birds Short term dietary LC50/LD50 > 5300 mg/kg feed
Earthworms Acute 14 day LD50 > 1000 mg kg-1
Fish Chronic 21 day NOEC 0.00025 mg l-1
Fish Acute 96 hour LC50 0.00021 mg l-1
Honeybees Acute 48 hour LD50 0.038 μg bee-1
Mammals Acute oral LD50 20 mg kg-1
Mammals Short term dietary NOEL 10 ppm diet
Mammals Short term dietary NOEL 0.7 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.105 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.00016 mg kg-1
Bio-concentration factor CT50 Not available days
Bio-concentration factor BCF 1950

Related targets

Target Name RScore (About this table)
CYP3A4 87(1,1,1,7) Details
CYP2D6 83(1,1,1,3) Details
glutathione S transferase 57(0,1,3,17) Details
Acetylcholinesterase 45(0,1,1,15) Details
catalase 39(0,1,2,4) Details
superoxide dismutase 38(0,1,2,3) Details
acid phosphatase 32(0,1,1,2) Details
alkaline phosphatase 32(0,1,1,2) Details
HC5 23(0,0,3,8) Details
Salvador 21(0,0,2,11) Details
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