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triadimefon

Identification (Source:EPA,EU)

ID	552
Name	triadimefon
CAS	43121-43-3
IUPAC
Inchi	InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3
CIPAC	352
EPA Code	109901
Formula	C14H16ClN3O2
SMILES	CC(C)(C)C(=O)C(N1C=NC=N1)OC2=CC=C(C=C2)Cl
Status	Not Approved

Classification

Mode of Action	Systemic with protective, curative and eradicant action. Disrupts membrane function.
Pesticide Type	Fungicide, Metabolite
Chemical Group	Triazole
Classification	conazole fungicides (triazoles)

Properties (Source:PubChem)

Molecular Weight	293.8
Physical State	Colourless crystals
AlogP	3.639
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	294.99
Polar Surface Area	57.01

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	2.01 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.1 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	7.16 mg l-1
Birds	Acute		LD50	> 2000 mg kg-1
Birds	Short term dietary		LC50/LD50	> 880 mg/kg bw/day
Earthworms	Acute	14 day	LD50	50 mg kg-1
Fish	Chronic	21 day	NOEC	0.017 mg l-1
Fish	Acute	96 hour	LC50	4.08 mg l-1
Honeybees	Acute	48 hour	LD50	25 μg bee-1
Mammals	Acute oral		LD50	300 mg kg-1
Mammals	Short term dietary		NOEL	300 ppm diet
	Bio-concentration factor		BCF	64.0
	Bio-concentration factor		CT50	0.6 days

Related targets

Target Name	RScore (About this table)
dopamine transporter	356(4,5,5,6)	Details
Krox20	86(1,1,1,6)	Details
11 beta HSD1	82(1,1,1,2)	Details
PPARgamma	82(1,1,1,2)	Details
hexose 6 phosphate dehydrogenase	81(1,1,1,1)	Details
HSD1	81(1,1,1,1)	Details
adenylate cyclase	81(1,1,1,1)	Details
CYP17	81(1,1,1,1)	Details
cytochrome P450 (protein family or complex)	149(0,4,7,14)	Details
demethylase	73(0,2,3,8)	Details
chitinase	35(0,1,1,5)	Details
CRABPI	35(0,1,1,5)	Details
tyrosine hydroxylase	31(0,1,1,1)	Details

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