| Name | dopamine transporter |
|---|---|
| Synonyms | DA transporter; DAT1; DAT; DAT 1; Dopamine transporter; SLC6A3; Sodium dependent dopamine transporter; Dopamine transporters… |
| Name | triadimefon |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8806838 | Walker QD, Mailman RB: Triadimefon and triadimenol: effects on monoamine uptake and release. Toxicol Appl Pharmacol. 1996 Aug;139(2):227-33. To test the hypothesis that triadimefon and triadimenol are indirect-acting agonists, the present studies examined their abilities to inhibit monoamine uptake, bind to the dopamine transporter, and stimulate efflux in rat brain tissue, in vitro. |
162(2,2,2,2) | Details |
| 16246478 | Gagnaire F, Micillino JC: Effects of triadimefon on extracellular HVA and 5-HIAA in adult rat striatum. Toxicology. 2006 Jan 16;217(2-3):91-104. Epub 2005 Oct 24. Triadimefon has been shown to inhibit monoamine uptake, bind to the (DA) transporter, and stimulate efflux in rat brain tissue, in vitro. |
112(1,2,2,2) | Details |
| 9339824 | Ikaiddi MU, Akunne HC, Soliman KF: Behavioral and neurochemical effects of acute and repeated administration of triadimefon in the male rat. Neurotoxicology. 1997;18(3):771-80. |
0(0,0,0,0) | Details |
| 15451308 | Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA: The effect of developmental exposure to the fungicide triadimefon on behavioral sensitization to triadimefon during adulthood. Toxicol Appl Pharmacol. 2004 Oct 1;200(1):54-63. Triadimefon (TDF) is a triazole fungicide that acts as an indirect (DA) agonist by binding to the dopamine transporter (DAT) and increasing levels of synaptic DA. |
81(1,1,1,1) | Details |
| 14592684 | Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA: Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon. Pharmacol Biochem Behav. 2003 Sep;76(2):315-26. TDF induction/expression of behavioral sensitization was associated with long-term, perhaps permanent modulation of dopaminergic function that included increases in striatal and DA turnover, increases in medial prefrontal cortex (mPFC) dopamine transporter (DAT) binding, as well as decreases in DA D1 and increases in DA D2 and DAT receptor binding that appeared to target the nucleus accumbens shell (NAs) subregion. |
1(0,0,0,1) | Details |