| Name | aryl hydrocarbon receptor |
|---|---|
| Synonyms | AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs… |
| Name | carbaryl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17220082 | Casado S, Alonso M, Herradon B, Tarazona JV, Navas J: Activation of the aryl hydrocarbon receptor by carbaryl: Computational evidence of the ability of carbaryl to assume a planar conformation. Environ Toxicol Chem. 2006 Dec;25(12):3141-7. |
445(5,6,7,10) | Details |
| 9853009 | Denison MS, Phelan D, Winter GM, Ziccardi MH: Carbaryl, a insecticide, is a ligand for the hepatic Ah (dioxin) receptor. Toxicol Appl Pharmacol. 1998 Oct;152(2):406-14. |
307(3,5,5,7) | Details |
| 17553063 | Boronat S, Casado S, Navas JM, Pina B: Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand. FEBS J. 2007 Jul;274(13):3327-39. Epub 2007 Jun 6. |
276(3,4,4,6) | Details |
| 9858662 | Sandoz C, Lesca P, Carpy A, Laguionie M, Narbonne JF: Effects of carbaryl and naphthalene on rat hepatic CYP1A1/2: potential binding to Ah receptor and 4S benzo (a) pyrene-binding protein. Int J Mol Med. 1998 Nov;2(5):615-23. |
163(2,2,2,3) | Details |
| 10620349 | Sandoz C, Lesca P, Narbonne JF, Carpy A: Molecular characteristics of carbaryl, a CYP1A1 gene inducer. Arch Biochem Biophys. 2000 Jan 1;373(1):275-80. This study demonstrates the inability of carbaryl to compete with 2,3,7,8-tetrachlorodibenzo-p-dioxin for binding to the rat aryl hydrocarbon (dioxin) receptor. |
113(1,2,2,3) | Details |
| 19447539 | Henseler RA, Romer EJ, Sulentic CE: Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region. Toxicology. 2009 Jun 30;261(1-2):9-18. Epub 2009 Mar 31. Utilizing a CH12.LX mouse B-cell line that stably expresses a 3'IgHRR-regulated transgene, we identified an inhibition of both 3'IgHRR activation and IgH protein expression by the non-dioxin AhR activators indolo (3,2-b) carbazole, primaquine, carbaryl, and which followed a rank order potency for AhR activation supporting a role of the AhR in the transcriptional regulation of the 3'IgHRR and IgH expression. |
85(1,1,1,5) | Details |
| 9169082 | Ledirac N, Delescluse C, de Sousa G, Pralavorio M, Lesca P, Amichot M, Berge JB, Rahmani R: Carbaryl induces CYP1A1 gene expression in HepG2 and HaCaT cells but is not a ligand of the human hepatic Ah receptor. Toxicol Appl Pharmacol. 1997 May;144(1):177-82. When alpha-naphthoflavone, a partial Ah receptor (AhR) antagonist, and 8-methoxypsoralen, which interferes with the binding of activated AhR to the xenobiotic responsive element (XRE), were added to the cultures, CYP1A1 induction was suppressed. |
1(0,0,0,1) | Details |
| 9820645 | Delescluse C, Ledirac N, de Sousa G, Pralavorio M, Lesca P, Rahmani R: Cytotoxic effects and induction of cytochromes P450 1A1/2 by insecticides, in hepatic or epidermal cells: binding capability to the Ah receptor. Toxicol Lett. 1998 Aug;96-97:33-9. We therefore tested the comparative acute and chronic toxicity of chemicals belonging to the major insecticides families (DDT, malathion and tetrachlorvinphos, carbaryl, cypermethrin, diflubenzuron), in hepatocytes, HepG2 and HaCaT cell lines. |
1(0,0,0,1) | Details |
| 11226373 | Delescluse C, Ledirac N, Li R, Piechocki MP, Hines RN, Gidrol X, Rahmani R: Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells. Biochem Pharmacol. 2001 Feb 15;61(4):399-407. |
0(0,0,0,0) | Details |
| 17431010 | Bohonowych JE, Denison MS: Persistent binding of ligands to the aryl hydrocarbon receptor. . Toxicol Sci. 2007 Jul;98(1):99-109. Epub 2007 Apr 12. Preincubation of cytosol with 2,3,7,8-tetrachlorodibenzofuran, carbaryl, or primaquine, prior to the addition of [(3) H] TCDD, shifted the apparent IC (50) of these compounds as competitive AhR ligands by approximately 10- to 50-fold. |
37(0,1,1,7) | Details |