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carbaryl

Identification (Source:EPA,EU)

ID	132
Name	carbaryl
CAS	63-25-2
IUPAC	1-naphthyl methylcarbamate
Inchi	InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
CIPAC	26
EPA Code	056801
Formula	C12H11NO2
SMILES	c12c(OC(NC)=O)cccc1cccc2
Status	Not Approved

Classification

Mode of Action	Stomach and contact activity with slight systemic properties. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type	Insecticide, Plant growth regulator
Chemical Group	Carbamate
Classification	carbamate insecticides carbamate acaricides growth inhibitors

Properties (Source:PubChem)

Molecular Weight	201.22
Physical State	White-grey powder
AlogP	2.502
H-Bond Donor	1
H-Bond Acceptor	2
Surface Area	196.07
Polar Surface Area	38.33

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.6 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.0057 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.0064 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.25 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	13.7 mg l-1
Birds	Acute		LD50	> 2000 mg kg-1
Birds	Short term dietary		LC50/LD50	> 1000 mg/kg bw/day
Earthworms	Acute	14 day	LD50	< 4 mg kg-1
Fish	Acute	96 hour	LC50	2.6 mg l-1
Fish	Chronic	21 day	NOEC	0.21 mg l-1
Honeybees	Acute	48 hour	LD50	0.14 μg bee-1
Mammals	Acute oral		LD50	614 mg kg-1
Mammals	Short term dietary		NOEL	3.73 mg kg-1
Sediment dwelling organisms	Acute	96 hour	LC50	0.13 mg l-1
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	44

Related targets

Target Name	RScore (About this table)
Acetylcholinesterase	3478(27,58,84,258)	Details
serum cholinesterase	2851(22,47,74,206)	Details
aryl hydrocarbon receptor	1428(15,21,22,43)	Details
interleukin 2	425(4,7,7,15)	Details
cytochrome P450 (protein family or complex)	425(4,6,10,25)	Details
CYP1A1	379(3,6,11,24)	Details
demethylase	293(3,4,6,13)	Details
CYP2B6	244(3,3,3,4)	Details
aryl hydrocarbon receptor nuclear translocator	193(2,3,3,3)	Details
interferon (protein family or complex)	164(2,2,2,4)	Details
CYP3A4	137(1,2,4,17)	Details
albumin	133(1,2,5,8)	Details
protein phosphatase inhibitor 1	112(1,2,2,2)	Details
Microsomal monooxygenase	112(1,2,2,2)	Details
glucose 6 phosphatase	99(1,1,4,4)	Details
beta glucuronidase	93(1,1,2,8)	Details
protein a	92(1,1,2,7)	Details
SRBC	90(1,1,2,5)	Details
transferase	85(1,1,1,5)	Details
Egasyn	84(1,1,1,4)	Details
thyroid hormone receptor (protein family or complex)	82(1,1,1,2)	Details
kynurenine formamidase	82(1,1,1,2)	Details
protein phosphatase	82(1,1,1,2)	Details
adenylate cyclase	81(1,1,1,1)	Details
yl 1	81(1,1,1,1)	Details
steroidogenic acute regulatory protein	81(1,1,1,1)	Details
adenylyl cyclase	81(1,1,1,1)	Details
serine threonine protein phosphatase	81(1,1,1,1)	Details
sulfatase	81(1,1,1,1)	Details
c fos	81(1,1,1,1)	Details
CHIT	81(1,1,1,1)	Details
MIP 2	81(1,1,1,1)	Details
cytochrome P450 1A2	85(0,2,4,15)	Details
N acetyltransferase	75(0,2,4,5)	Details
aryl hydrocarbon hydroxylase	75(0,2,4,5)	Details
aspartate aminotransferase	63(0,2,2,3)	Details
glutathione S transferase	57(0,1,4,12)	Details
hydroxyindole O methyltransferase	50(0,1,4,5)	Details
epoxide hydrolase	44(0,1,3,4)	Details
lactate dehydrogenase (protein family or complex)	40(0,1,2,5)	Details
Koc	38(0,1,2,3)	Details
neuropathy target esterase	35(0,1,1,5)	Details
CARB	33(0,1,1,3)	Details
glutathione reductase	33(0,1,1,3)	Details
beta glucosidase	32(0,1,1,2)	Details
sodium channel (protein family or complex)	32(0,1,1,2)	Details

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