| Name | serum cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | carbaryl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1488778 | Casale GP, Bavari S, Gold RE, Vitzthum EF: Inhibition of interleukin-2-stimulated enhancement of human natural killer (NK) cell activity by carbaryl, an anticholinesterase insecticide. Toxicol Lett. 1992 Dec;63(3):299-311. |
32(0,1,1,2) | Details |
| 3083675 | Branch RA, Jacqz E: Is carbaryl as safe as its reputation? Does it have a potential for causing chronic neurotoxicity in humans?. Am J Med. 1986 Apr;80(4):659-64. Short-term studies in animal species and humans confirm that carbaryl can cause toxicity due to cholinesterase inhibition. |
31(0,1,1,1) | Details |
| 1906943 | Banerjee J, Ghosh P, Mitra S, Ghosh N, Bhattacharya S: Inhibition of human fetal brain acetylcholinesterase: marker effect of neurotoxicity. J Toxicol Environ Health. 1991 Jul;33(3):283-90. In vitro inhibition of cerebellar AChE with two commercial pesticides, Metacid-50 (O,O-dimethyl p-nitrophenyl phosphorothioate) and carbaryl (N-methyl naphthyl-1- were compared with pure anticholinesterase agents, diisopropylfluorophosphate (DFP) and physostigmine (eserine). |
31(0,1,1,1) | Details |
| 17504769 | McDaniel KL, Padilla S, Marshall RS, Phillips PM, Podhorniak L, Qian Y, Moser VC: Comparison of acute neurobehavioral and cholinesterase inhibitory effects of N-methylcarbamates in rat. Toxicol Sci. 2007 Aug;98(2):552-60. Epub 2007 May 15. The chemicals tested were carbaryl, carbofuran, formetanate, methiocarb, methomyl, oxamyl, and propoxur. |
3(0,0,0,3) | Details |
| 11742736 | Andreou VG, Clonis YD: A portable fiber-optic pesticide biosensor based on immobilized cholinesterase and sol-gel entrapped bromcresol purple for in-field use. Biosens Bioelectron. 2002 Jan;17(1-2):61-9. A fiber-optic biosensor for the detection and determination of the pesticides carbaryl and dichlorvos was developed. |
2(0,0,0,2) | Details |
| 17223355 | Sun J, Lynn BC: Development of a MALDI-TOF-MS method to identify and quantify butyrylcholinesterase inhibition resulting from exposure to organophosphate and pesticides. J Am Soc Mass Spectrom. 2007 Apr;18(4):698-706. Epub 2007 Jan 16. Excellent linearity (r2 > 0.98) between the normalized abundance ratios (NARs) and OP concentrations or logarithm of carbaryl concentration was obtained. |
2(0,0,0,2) | Details |
| 8642625 | Wilson BW, Padilla S, Henderson JD, Brimijoin S, Dass PD, Elliot G, Jaeger B, Lanz D, Pearson R, Spies R: Factors in standardizing automated cholinesterase assays. J Toxicol Environ Health. 1996 Jun 7;48(2):187-95. |
2(0,0,0,2) | Details |
| 15663293 | Choi J, Hodgson E, Rose RL: Inhibition of trans-permethrin hydrolysis in human liver fractions by chloropyrifos oxon and carbaryl. Drug Metabol Drug Interact. 2004;20(4):233-46. Carbaryl, a known anticholinesterase agent, showed non-competitive inhibition kinetics, with Ki values two orders of magnitude higher than those for chlorpyrifos oxon. |
31(0,1,1,1) | Details |
| 2109732 | Forgue MF, Pipy B, Beraud M, Souqual MC, Combis JM: 1-naphthyl N-methyl effect on intra- and extracellular concentrations of metabolites, and on the chemiluminescence generation by mouse peritoneal macrophages. Int J Immunopharmacol. 1990;12(2):155-63. 1-Naphthyl N-methyl (carbaryl), potent insecticide with anticholinesterase activity, was tested for its ability to affect mouse peritoneal macrophages in particular (AA) metabolism and oxidative burst. |
31(0,1,1,1) | Details |
| 6777420 | Basol MS, Eren S, Sadar MH: Comparative toxicity of some pesticides on human health and some aquatic species. J Environ Sci Health B. 1980;15(6):993-1004. Inhibition studies have been carried on the hydrolysis reactions catalyzed by cholinesterases taken from electric eel, human and horse serums by Sevin, Aldrin and Malathion. |
2(0,0,0,2) | Details |
| 9732468 | Gruber SJ, Munn MD: Organophosphate and insecticides in agricultural waters and cholinesterase (ChE) inhibition in common carp (Cyprinus carpio). Arch Environ Contam Toxicol. 1998 Oct;35(3):391-6. The depressed ChE activity in brain tissue of Royal Lake carp was in response to ChE-inhibiting insecticides detected in water samples in the weeks prior to tissue sampling; the most frequently detected insecticides included chlorpyrifos, azinphos-methyl, carbaryl, and ethoprop. |
2(0,0,0,2) | Details |
| 105821 | Pipy B, Gaillard D, Declume C, Derache R: [Effect of blockade or stimulation of the reticuloendothelial system on the blood clearance kinetics of the anticholinesterase insecticide carbaryl in the rat]. C R Acad Sci Hebd Seances Acad Sci D. 1978 Oct 30;287(11):1059-61. |
31(0,1,1,1) | Details |
| 105127 | Pipy B, Beraud M, Gaillard D: [Relationship between the phagocytic inhibition of the rat reticuloendothelial system and the anticholinesterasic effect of an insecticide, Carbaryl (author's transl)]. J Physiol. 1978;74(4):379-85. Phagocytic activity of the reticuloendothelial system (RES) and blood cholinesterase activity were determined in male rats after veinous administrations of carbaryl and 1-naphthol, a carbaryl metabolite. |
31(0,1,1,1) | Details |
| 16753348 | Caselli F, Gastaldi L, Gambi N, Fabbri E: In vitro characterization of cholinesterases in the earthworm Eisenia andrei. Comp Biochem Physiol C Toxicol Pharmacol. 2006 Aug;143(4):416-21. Epub 2006 Apr 28. ASCh and PSCh hydrolysis were significantly inhibited by eserine (IC50 values were 1.44 x 10 (-8) and 1.20 x 10 (-8) M, respectively) and by carbaryl (IC50 values of 5.75 x 10 (-9) and 4.79 x 10 (-9) M). |
2(0,0,0,2) | Details |
| 19442821 | Gordon CJ, Ward WO: A multianalyte profile of serum proteins to screen for toxicological effects of anticholinesterase insecticides in the rat. Neurotoxicology. 2009 May;30(3):377-81. Epub 2009 Feb 24. |
2(0,0,0,2) | Details |
| 3083676 | Branch RA, Jacqz E: Subacute neurotoxicity following long-term exposure to carbaryl. . Am J Med. 1986 Apr;80(4):741-5. It can induce acute cholinesterase poisoning, which is rapidly reversible on discontinuation of exposure. |
2(0,0,0,2) | Details |
| 17454568 | Mack CM, Gordon CJ: Differential sensitivity to anticholinesterase insecticides in the juvenile rat: effects on thermoregulation. J Toxicol Environ Health A. 2007 Mar 1;70(5):439-44. The PND 17 pups were then dosed by oral gavage with the OP chlorpyrifos (CHP) (1, 5, 10, or 15 mg/kg) or the CB carbaryl (CAR) (10, 20, 80, 120, or 160 mg/kg) or the corn oil vehicle. |
2(0,0,0,2) | Details |
| 105427 | Declume C, Benard P: [Pharmacokinetic study of 14C-carbaryl in pregnant mice (author's transl)] . Toxicol Eur Res. 1978 May;1(3):173-80. The distribution of a single oral dose of 1-naphthyl-N-methyl 14C- (Carbaryl), a cholinesterase inhibitor, in pregnant mice (18th day) was determined by whole-body autoradiography and 14C-activity counting of main organs. |
31(0,1,1,1) | Details |
| 16704049 | Scholz NL, Truelove NK, Labenia JS, Baldwin DH, Collier TK: Dose-additive inhibition of chinook salmon acetylcholinesterase activity by mixtures of organophosphate and insecticides. Environ Toxicol Chem. 2006 May;25(5):1200-7. Anticholinesterase insecticides commonly co-occur in the environment. We extracted AChE from the olfactory nervous system of chinook salmon (Oncorhynchus tshawytscha) and investigated the inhibitory effects of organophosphates (the oxon derivatives of diazinon, chlorpyrifos, and malathion) and carbamates (carbaryl and carbofuran), alone and in two-way combinations. |
2(0,0,0,2) | Details |
| 12873401 | Valbonesi P, Sartor G, Fabbri E: Characterization of cholinesterase activity in three bivalves inhabiting the North Adriatic sea and their possible use as sentinel organisms for biosurveillance programmes. Sci Total Environ. 2003 Aug 1;312(1-3):79-88. Significant inhibition of ChE activity by eserine, carbaryl, and ethyl-paraoxon was observed in gills of O. edulis and M. galloprovincialis. |
2(0,0,0,2) | Details |
| 9585096 | Mortensen SR, Hooper MJ, Padilla S: Rat brain acetylcholinesterase activity: developmental profile and maturational sensitivity to and organophosphorus inhibitors. Toxicology. 1998 Jan 16;125(1):13-9. A growing body of evidence indicates that young animals exhibit an increased susceptibility to the lethal effects of cholinesterase (ChE)-inhibiting insecticides. IC50s (the concentration of compound that inhibits 50% of the AChE activity in 30 min at 26 degrees C) defined concomitantly for postnatal day 4 and adult brain AChE using either aldicarb, carbaryl, chlorpyrifos-oxon or malaoxon were virtually identical at both ages with average IC50 values being: aldicarb = 2.4 microM, carbaryl = 1.7 microM, chlorpyrifos-oxon = 4.9 nM and malaoxon = 140 nM. |
2(0,0,0,2) | Details |
| 8161944 | Dawson RM: Rate constants of carbamylation and decarbamylation of acetylcholinesterase for physostigmine and carbaryl in the presence of an oxime. Neurochem Int. 1994 Feb;24(2):173-82. The results extend those in a recent report by other authors who studied the half-life of carbamylation for acetylcholinesterase and butyrylcholinesterase in an attempt to understand the mechanism by which oximes increase the toxicity of carbaryl in vivo. |
31(0,1,1,1) | Details |
| 4633216 | Sideroff SI, Santolucito JA: Behavioral and physiological effects of the cholinesterase inhibitor carbaryl (1-naphthyl methylcarbamate). Physiol Behav. 1972 Sep;9(3):459-62. |
31(0,1,1,1) | Details |
| 11881970 | Sachana M, Flaskos J, Nikolaidis E, Hargreaves A, Alexaki-Tzivanidou E: Inhibition of rat platelet uptake by chlorpyrifos and carbaryl. Pharmacol Toxicol. 2001 Oct;89(4):195-200. The activities of brain acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BuChE) were also determined. |
2(0,0,0,2) | Details |
| 8349949 | Casale GP, Vennerstrom JL, Bavari S, Wang TL: Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected and organophosphate insecticides and congeners of carbaryl. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):199-215. The anticholinesterase (antiCHE) insecticides, a large family of pesticides used extensively throughout the world, inhibit serine hydrolases by carbamylating or phosphorylating a serine residue at the catalytic site. |
1(0,0,0,1) | Details |
| 16182429 | Gordon CJ, Herr DW, Gennings C, Graff JE, McMurray M, Stork L, Coffey T, Hamm A, Mack CM: Thermoregulatory response to an organophosphate and insecticide mixture: testing the assumption of dose-additivity. Toxicology. 2006 Jan 5;217(1):1-13. Epub 2005 Sep 22. This study assessed if there is an interaction between mixtures of the anticholinesterase insecticides chlorpyrifos (CHP) and carbaryl (CAR) using hypothermia and cholinesterase (ChE) inhibition as toxicological endpoints. |
31(0,1,1,1) | Details |
| 8473601 | Karunaratne KM, Plapp FW Jr: Biochemistry and genetics of thiodicarb resistance in the house fly (Diptera: Muscidae). J Econ Entomol. 1993 Apr;86(2):258-64. Bioassays with several strains revealed that a thiodicarb-resistant strain was also resistant to carbaryl and to several organophosphates. Cholinesterase assays showed that the enzyme of the resistant strain was several times more resistant to inhibition by carbamates than the enzyme of a susceptible strain or a strain with only metabolic resistance to insecticides. |
1(0,0,0,1) | Details |
| 116071 | Hill EF: Cholinesterase activity in Japanese quail dusted with carbaryl. . Lab Anim Sci. 1979 Jun;29(3):349-52. |
13(0,0,2,3) | Details |
| 3149406 | Dobreva V, Kaloianova F: [Changes in the hexobarbital sleep and serum cholinesterase activity of rats treated with carbaryl]. Probl Khig. 1988;13:109-14. |
13(0,0,2,3) | Details |
| 4209143 | Smith RL: The estimation of serum cholinesterase in the presence of anti-cholinesterase insecticides. Clin Chim Acta. 1974 May 17;52(3):315-9. |
1(0,0,0,1) | Details |
| 4201796 | Cranmer M, Peoples A: Determination of trace quantities of anticholinesterase pesticides. Anal Biochem. 1973 Sep;55(1):255-65. |
1(0,0,0,1) | Details |
| 15690 | Lee MK, Serat WF: A simple method for cholinesterase determination using an expanded scale pH meter. Bull Environ Contam Toxicol. 1977 Mar;17(3):331-41. |
1(0,0,0,1) | Details |
| 83128 | Golbs S, Fuchs V, Leipner E, Huttel I: [The effect of pesticide combinations in laboratory rats. Arch Exp Veterinarmed. 1978;32(4):569-77. After oral administration of pesticides Parathion-methyl, Carbaryl, Lindane and their combinations were investigated the activities of enzyme SGOT, SGPT, Alkaline Phosphatase and Cholinesterase. |
12(0,0,2,2) | Details |
| 14709383 | Kok FN, Hasirci V: Determination of binary pesticide mixtures by an acetylcholinesterase- oxidase biosensor. Biosens Bioelectron. 2004 Feb 15;19(7):661-5. Enzyme immobilized membrane was used in the detection of anti-cholinesterase activity of aldicarb (AS), carbofuran (CF) and carbaryl (CL), as well as two mixtures, (AS+CF) and (AS+CL). |
8(0,0,1,3) | Details |
| 10794391 | Lockridge O, Masson P: Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk. Neurotoxicology. 2000 Feb-Apr;21(1-2):113-26. Butyrylcholinesterase (BChE) scavenges low doses of organophosphorus (for example, paraoxon) and pesticides (for example, carbaryl) and in this way protects people from the toxic effects of these poisons. |
7(0,0,1,2) | Details |
| 19161234 | Overmyer JP, Smith PF, Kellock KA, Kwon JW, Armbrust KL: Assessment of the toxicological interaction of with cholinesterase inhibiting insecticides in aquatic insects using the black fly, Simulium vittatum IS-7. Environ Toxicol. 2009 Jan 22. In this study, the interactive effect of (SSRI) in binary combinations with carbaryl insecticide) and diazinon (organophosphate insecticide) was assessed using a 48-h acute toxicity test with black fly larvae, Simulium vittatum IS-7. |
1(0,0,0,1) | Details |
| 17723768 | Arduini F, Ricci F, Tuta CS, Moscone D, Amine A, Palleschi G: Detection of carbamic and organophosphorous pesticides in water samples using a cholinesterase biosensor based on Prussian Blue-modified screen-printed electrode. Anal Chim Acta. 2006 Nov 24;580(2):155-62. Epub 2006 Jul 29. AChE-based biosensors have demonstrated a higher sensitivity towards aldicarb (50% inhibition with 50 ppb) and carbaryl (50% inhibition with 85 ppb) while BChE biosensors have shown a higher affinity towards paraoxon (50% inhibition with 4 ppb) and chlorpyrifos-methyl oxon (50% inhibition with 1 ppb). |
1(0,0,0,1) | Details |
| 18704829 | Nong A, Tan YM, Krolski ME, Wang J, Lunchick C, Conolly RB, Clewell HJ 3rd: Bayesian calibration of a physiologically based pharmacokinetic/pharmacodynamic model of carbaryl cholinesterase inhibition. J Toxicol Environ Health A. 2008;71(20):1363-81. Carbaryl, an N-methyl (NMC), is a common insecticide that reversibly inhibits neuronal cholinesterase activity. |
275(3,4,4,5) | Details |
| 112721 | Pipy B, Gaillard D, Derache: Effect of blockade of the reticuloendothelial system on the carbaryl toxicity in the rat. Toxicology. 1979 Feb;12(2):135-42. Carbaryl rapidly inhibits cholinesterase; the time of "reactivation" of this enzyme increases with the administered dose. |
224(2,4,4,4) | Details |
| 2129284 | Takahashi RN, Poli A, Morato GS, Lima TC, Zanin M: Behavioral and biochemical changes following repeated administration of carbaryl to aging rats. Braz J Med Biol Res. 1990;23(9):879-82. Administration of carbaryl (50 mg/kg) by gavage daily for 30 days resulted in a reduction of locomotor activity in the open-field and in an inhibition of cholinesterase activity within 30 min after the last treatment. |
193(2,3,3,3) | Details |
| 405055 | Zinkl JG, Henny CJ, DeWeese LR: Brain cholinesterase activities of birds from forests sprayed with trichlorfon (Dylox) and carbaryl (Sevin-4-oil). Bull Environ Contam Toxicol. 1977 Apr;17(4):379-86. |
7(0,0,1,2) | Details |
| 1459653 | Ghosh S, Bhattacharya S: Elevation of C-reactive protein in serum of Channa punctatus as an indicator of water pollution. Indian J Exp Biol. 1992 Aug;30(8):736-7. The compound, carbaryl demonstrated a biphasic response to CRP level which may be correlated with the reversible type of anticholinesterase property of this compound while Metacid-50 is an irreversible type of anticholinesterase agent. |
6(0,0,1,1) | Details |
| 15519728 | Hopkins WA, Winne CT, DuRant SE: Differential swimming performance of two natricine snakes exposed to a cholinesterase-inhibiting pesticide. Environ Pollut. 2005 Feb;133(3):531-40. Here, we explore the possibility that the swimming performance of neonate black swamp snakes (Seminatrix pygaea) and diamondback water snakes (Nerodia rhombifer) may be affected by exposure to carbaryl (2.5 and 5.0 mg/L). |
1(0,0,0,1) | Details |
| 11386719 | Beauvais SL, Jones SB, Parris JT, Brewer SK, Little EE: Cholinergic and behavioral neurotoxicity of carbaryl and cadmium to larval rainbow trout (Oncorhynchus mykiss). Ecotoxicol Environ Saf. 2001 May;49(1):84-90. Brain tissue was used to measure cholinesterase (ChE) activity, muscarinic cholinergic receptor (MChR) number, and MChR affinity. |
1(0,0,0,1) | Details |
| 1904531 | Takahashi RN, Poli A, Morato GS, Lima TC, Zanin M: Effects of age on behavioral and physiological responses to carbaryl in rats. Neurotoxicol Teratol. 1991 Jan-Feb;13(1):21-6. Activity of blood cholinesterase was reduced in young and mature rats at 30 and 60 min following carbaryl exposure. |
193(2,3,3,3) | Details |
| 1412499 | Lieske CN, Clark JH, Maxwell DM, Zoeffel LD, Sultan WE: Studies of the amplification of carbaryl toxicity by various oximes. Toxicol Lett. 1992 Sep;62(2-3):127-37. Our hypothesis is that certain oximes act as allosteric effectors of cholinesterases in carbaryl poisoning, resulting in enhanced inhibition rates and potentiation of carbaryl toxicity. |
113(1,2,2,3) | Details |
| 6411799 | Falzon M, Fernandez Y, Cambon-Gros C, Mitjavila S: Influence of experimental hepatic impairment on the toxicokinetics and the anticholinesterase activity of carbaryl in the rat. J Appl Toxicol. 1983 Apr;3(2):87-9. The variations in the primary toxicity of carbaryl were assessed by measuring the inhibition of the plasma and erythrocyte cholinesterases and by evaluation of the lethal doses. |
89(1,1,2,4) | Details |
| 16649625 | Jyothi B, Narayan G: Study of Serum Cholinesterase levels in fish Clarias batrachus (Linn.) exposed to pesticides carbaryl and phorate. J Environ Sci Eng. 2004 Oct;46(4):274-6. |
7(0,0,1,2) | Details |
| 3011687 | de Maroussem D, Pipy B, Beraud M, Souqual MC, Forgue MF: The effect of carbaryl on the arachidonic acid metabolism and production by mouse resident peritoneal macrophages challenged by zymosan. Int J Immunopharmacol. 1986;8(2):155-66. Carbaryl, a broad spectrum insecticide with anticholinesterase activity, was tested for its ability to disturb resident peritoneal macrophages stimulated by opsonized zymosan. |
6(0,0,1,1) | Details |
| 6138014 | Michalek H, Nemesio R, Meneguz A, Bisso GM: Interactions between anticholinesterase agents and neuroleptics in terms of cholinesterase inhibition in brain and other tissues of rats. Arch Toxicol Suppl. 1983;6:386-90. CPZ was found to potentiate slightly the effects of Mevinphos but did not interact with Carbaryl, Diazinon or Azinphos. |
1(0,0,0,1) | Details |
| 4357849 | Cranmer MF, Peoples AJ: Measurement of blood cholinesterase activity in laboratory animals utilizing dimethylbutyl as a substrate. Lab Anim Sci. 1973 Dec;23(6):881-4. |
1(0,0,0,1) | Details |
| 1507271 | Ehrich M, Correll L, Strait J, McCain W, Wilcke J: Toxicity and toxicokinetics of carbaryl in chickens and rats: a comparative study. J Toxicol Environ Health. 1992 Aug;36(4):411-23. A dose of 900 mg/kg to chickens and 70 mg/kg to rats caused equivalent inhibition of brain cholinesterase activities (57% +/- 6 and 47% +/- 4, respectively) 60 min after administration, which was the time of maximal cholinergic signs. |
1(0,0,0,1) | Details |
| 16293993 | Al-Jobory MM, Mohammad FK: Validation of an electrometric blood cholinesterase measurement in goats. J Vet Sci. 2005 Dec;6(4):299-303. The organophosphorus insecticides dichlorvos and diazinon at 0.5-4 microM and the insecticide carbaryl at 5-20 microM in the reaction mixture significantly inhibited plasma (13.7-85.5%) and erythrocyte (16.4-71.9%) cholinesterases in vitro in a concentration-dependent manner. |
87(1,1,1,7) | Details |
| 6789785 | Mount ME, Oehme FW: Diagnostic criteria for carbaryl poisoning in sheep. Arch Environ Contam Toxicol. 1981 Jul;10(4):483-95. Sheep dying acutely had higher levels of carbaryl and greater than or equal to 50% inhibition of brain cholinesterase activity, while sheep with prolonged death had lower carbaryl levels and less cholinesterase inhibition. |
87(1,1,2,2) | Details |
| 6815834 | Fernandez Y, Falzon M, Cambon-Gros C, Mitjavila S: Carbaryl tricompartmental toxicokinetics and anticholinesterase activity. Toxicol Lett. 1982 Oct;13(3-4):253-8. |
6(0,0,1,1) | Details |
| 3101772 | Zinkl JG, Shea PJ, Nakamoto RJ, Callman J: Brain cholinesterase activity of rainbow trout poisoned by carbaryl. Bull Environ Contam Toxicol. 1987 Jan;38(1):29-35. |
6(0,0,1,1) | Details |
| 4205301 | Gundu Rao HR, Anders MW: Inhibition of microsomal drug metabolism by anticholinesterase insecticides. Bull Environ Contam Toxicol. 1973 Jan;9(1):4-9. |
1(0,0,0,1) | Details |
| 10421485 | Satoh T, Suzuki S, Kawai N, Nakamura T, Hosokawa M: Toxicological significance in the cleavage of esterase-beta-glucuronidase complex in liver microsomes by organophosphorus compounds. Chem Biol Interact. 1999 May 14;119-120:471-8. From these in vivo and in vitro data, it is concluded that increase of the plasma beta-G level after OP administration is much more sensitive biomarker than cholinesterase inhibition to acute intoxication of OPs and carbamates. Similarly, insecticides such as carbaryl caused rapid increase of plasma beta-G level. |
1(0,0,0,1) | Details |
| 2731661 | Casale GP, Bavari S, Connolly JJ: Inhibition of human serum complement activity by diisopropylfluorophosphate and selected anticholinesterase insecticides. Fundam Appl Toxicol. 1989 Apr;12(3):460-8. Since the widely used anticholinesterase insecticides inhibit serine esterases, the present study evaluated potencies of carbaryl, carbofuran, dichlorvos, and paraoxon to inhibit C' activities of a panel of normal human sera. |
83(1,1,1,3) | Details |
| 15041264 | Ferrari A, Venturino A, de D'Angelo AM: Time course of brain cholinesterase inhibition and recovery following acute and subacute azinphosmethyl, parathion and carbaryl exposure in the goldfish (Carassius auratus). Ecotoxicol Environ Saf. 2004 Mar;57(3):420-5. |
83(1,1,1,3) | Details |
| 17950890 | Mwanza JC, Finley D, Spivey CL, Graff JE, Herr DW: Depression of the photic after discharge of flash evoked potentials by physostigmine, carbaryl and propoxur, and the relationship to inhibition of brain cholinesterase. Neurotoxicology. 2008 Jan;29(1):87-100. Epub 2007 Sep 14. |
82(1,1,1,2) | Details |
| 17197007 | Padilla S, Marshall RS, Hunter DL, Lowit A: Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):202-9. Epub 2006 Nov 15. |
82(1,1,1,2) | Details |
| 3133272 | L'Abbate N, Virgintino D, Ribatti D, Roncali L, Miccoli MG, Ambrosi L: [Effects of carbaryl on the morphogenesis of the extremities in chick embryos]. G Ital Med Lav. 1986 May-Jul;8(3-4):123-6. Experimental studies have been carried out to evaluate the effects of carbaryl (l.-naphthyl-methyl-- an anticholinesterase pesticide - on the morphogenesis and development of the chick embryo. |
6(0,0,1,1) | Details |
| 6787736 | Mount ME, Dayton AD, Oehme FW: Carbaryl residues in tissues and cholinesterase activities in brain and blood of rats receiving carbaryl. Toxicol Appl Pharmacol. 1981 Apr;58(2):282-96. |
6(0,0,1,1) | Details |
| 12385721 | Tang J, Cao Y, Rose RL, Hodgson E: In vitro metabolism of carbaryl by human cytochrome P450 and its inhibition by chlorpyrifos. Chem Biol Interact. 2002 Oct 20;141(3):229-41. Carbaryl is a widely used anticholinesterase insecticide. |
6(0,0,1,1) | Details |
| 404730 | Declume C, Benard P: [Autoradiographic study of the distribution of an anticholinesterase agent, 1-naphthyl-N-methyl [14C] in the pregnant rat] Toxicol Appl Pharmacol. 1977 Mar;39(3):451-60. |
1(0,0,0,1) | Details |
| 406567 | Schmid ER, Damboritz W, Markl P: [Radiometric determination of 11 pesticides in the nanogram and subnanongram ranges by means of cholinesterase inhibition]. Nahrung. 1977;21(4):311-7. The limit of detection for aldicarb, baygon, benomyl, bux, carbaryl, CIPC, matacil, phenmedipham and promecarb lies in the picogram range; that for barban and methomyl, in the nanogram range. |
1(0,0,0,1) | Details |
| 4154787 | Stevens JT, Greene FE: Alteration of hepatic microsomal metabolism of male mice by certain anticholinesterase insecticides. Bull Environ Contam Toxicol. 1974 Jun;11(6):538-44. |
1(0,0,0,1) | Details |
| 2380482 | Farage-Elawar M: Effects of in ovo injection of carbamates on chick embryo hatchability, esterase enzyme activity and locomotion of chicks. J Appl Toxicol. 1990 Jun;10(3):197-201. Brain acetylcholinesterase (AChE) and liver cholinesterase (ChE) were inhibited significantly during incubation in embryos dosed on day 15 with both carbaryl and aldicarb. |
81(1,1,1,1) | Details |
| 6774405 | Podolak M, Warchocki B: [Effect of toxobidine on the kinetics of cholinesterase inhibition reaction by chlorfenvinphos and carbaryl] Rocz Panstw Zakl Hig. 1980;31(2):25-31. |
81(1,1,1,1) | Details |
| 7875555 | Rigon AR, Reis M, Takahashi RN: Effects of carbaryl on some dopaminergic behaviors in rats. Gen Pharmacol. 1994 Oct;25(6):1263-7. Carbaryl significantly reduced blood cholinesterase activity and elevated blood levels and SGOT and SGPT activities. 4. |
81(1,1,1,1) | Details |
| 3937737 | Ray SK, Poddar MK: Central cholinergic-dopaminergic interaction in carbaryl-induced tremor. Eur J Pharmacol. 1985 Dec 17;119(3):251-3. Acute administration of the anticholinesterase agent carbaryl to rats produced a dose-dependent increase of tremors. |
6(0,0,1,1) | Details |
| 19362380 | Ferrari A, Lascano CI, Anguiano OL, D'Angelo AM, Venturino A: Antioxidant responses to azinphos methyl and carbaryl during the embryonic development of the toad Rhinella (Bufo) arenarum Hensel. Aquat Toxicol. 2009 Jun 4;93(1):37-44. Epub 2009 Mar 24. We studied the effects of the exposure to two anticholinesterase agents, the carbaryl and the organophosphate azinphos methyl, on the antioxidant defenses of developing embryos of the toad Rhinella (Bufo) arenarum. |
6(0,0,1,1) | Details |
| 18775593 | Laguerre C, Sanchez-Hernandez JC, Kohler HR, Triebskorn R, Capowiez Y, Rault M, Mazzia C: B-type esterases in the snail Xeropicta derbentina: an enzymological analysis to evaluate their use as biomarkers of pesticide exposure. Environ Pollut. 2009 Jan;157(1):199-207. Epub 2008 Sep 4. Specific cholinesterase and carboxylesterase activities were mainly obtained with acetylthiocholine (K (m)=77.2 mM; V (max)=38.2 mU/mg protein) and 1-naphthyl (K (m)=222 mM, V (max)=1095 mU/mg protein) substrates, respectively. Acetylcholinesterase activity was concentration-dependently inhibited by chlorpyrifos-oxon, dichlorvos, carbaryl and carbofuran (IC50=1.35x10 (-5)-3.80x10 (-8) M). |
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| 4624402 | Stevens JT, Stitzel RE, McPhillips JJ: Effects of anticholinesterase insecticides on hepatic microsomal metabolism. J Pharmacol Exp Ther. 1972 Jun;181(3):576-83. |
1(0,0,0,1) | Details |
| 7713347 | Ehrich M, Jortner BS, Padilla S: Comparison of the relative inhibition of acetylcholinesterase and neuropathy target esterase in rats and hens given cholinesterase inhibitors. Fundam Appl Toxicol. 1995 Jan;24(1):94-101. Inhibition of neuropathy target esterase (NTE, neurotoxic esterase) and acetylcholinesterase (AChE) activities was compared in brain and spinal cords of adult While Leghorn hens and adult male Long Evan rats 4-48 hr after administration of triortho-tolyl (TOTP po, 50-500 mg/kg to hens; 300-1000 mg/kg to rats), phenyl saligenin (PSP im 0.1-2.5 mg/kg to hens; 5-24 mg/kg to rats), mipafox (3-30 mg/kg ip to hens and rats), diisopropyl phosphorofluoridate (DFP sc, 0.25-1.0 mg/kg to hens; 1-3 mg/kg to rats), dichlorvos (5-60 mg/kg ip to hens; 600-2000 mg/kg to rats), and carbaryl (300-560 mg/kg ip to hens; 30-170 mg/kg to rats). |
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| 3140000 | Soderpalm-Berndes C, Onfelt A: The action of carbaryl and its metabolite alpha-naphthol on mitosis in V79 Chinese hamster fibroblasts. Mutat Res. 1988 Oct;201(2):349-63. Carbaryl inhibits cholinesterases and when tested, another cholinesterase inhibitor, diisopropylfluorophosphate, in combination with alpha-naphthol also increased the frequency of monopolar configuration in combination with cleavage. |
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| 6803679 | Leavitt JR, Gold RE, Holcslaw T, Tupy D: Exposure of professional pesticide applicators to carbaryl. . Arch Environ Contam Toxicol. 1982;11(1):57-62. It was determined, in vitro, that 10 (-3) M carbaryl would inhibit human serum (pseudocholinesterase) and erythrocyte acetylcholinesterase for at least 72 hr. |
81(1,1,1,1) | Details |
| 1916080 | Bavari S, Casale GP, Gold RE, Vitzthum EF: Modulation of interleukin-2-driven proliferation of human large granular lymphocytes by carbaryl, an anticholinesterase insecticide. Fundam Appl Toxicol. 1991 Jul;17(1):61-74. |
62(0,2,2,2) | Details |
| 6437015 | Knaak JB, Yee K, Ackerman CR, Zweig G, Fry DM, Wilson BW: Percutaneous absorption and dermal dose-cholinesterase response studies with parathion and carbaryl in the rat. Toxicol Appl Pharmacol. 1984 Nov;76(2):252-63. |
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| 8747743 | Moser VC: Comparisons of the acute effects of cholinesterase inhibitors using a neurobehavioral screening battery in rats. Neurotoxicol Teratol. 1995 Nov-Dec;17(6):617-25. The acute effects of two carbamates (carbaryl, aldicarb) and five organophosphates (OP) (chlorpyrifos, diazinon, parathion, fenthion, and diisopropyl fluorophosphate, or DFP) were evaluated on the day of dosing at the time of peak effect, at 1 and 3 days, and 1 week after dosing (oral gavage, in corn oil). |
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| 1627982 | Devinsky O, Kernan J, Bear DM: Aggressive behavior following exposure to cholinesterase inhibitors. . J Neuropsychiatry Clin Neurosci. 1992 Spring;4(2):189-94. |
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| 17324631 | Vioque-Fernandez A, de Almeida EA, Lopez-Barea J: Esterases as pesticide biomarkers in crayfish (Procambarus clarkii, Crustacea): tissue distribution, sensitivity to model compounds and recovery from inactivation. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):404-12. Epub 2007 Jan 30. The specific activities of acetyl- and butyrylcholinesterase and carboxylesterase were assayed in the digestive gland and in nervous and muscle tissues of the crayfish Procambarus clarkii. Carboxylesterase was inhibited by carbaryl and chlorpyrifos, but not by eserine and malathion. |
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| 8561923 | Chakravorty PP, Bose S, Joy VC, Bhattacharya S: Biomonitoring of anticholinesterase pesticides in the soil: usefulness of soil Collembola. Biomed Environ Sci. 1995 Sep;8(3):232-9. The impact of Methyl parathion and Carbaryl was evaluated on an ecologically important soil Collembola, Cyphoderus sp. |
1(0,0,0,1) | Details |
| 9577785 | Orsted KM, Dubay SA, Raisbeck MF, Siemion RS, Sanchez DA, Williams ES: Lack of relay toxicity in ferret hybrids fed carbaryl-treated prairie dogs. J Wildl Dis. 1998 Apr;34(2):362-4. Potential for relay toxicity was evaluated by analyzing ferret blood cholinesterase (CHe), prairie dog brain Che, and hepatic concentration. |
1(0,0,0,1) | Details |
| 18072155 | Mohammad FK, Alias AS, Ahmed OA: Electrometric measurement of plasma, erythrocyte, and whole blood cholinesterase activities in healthy human volunteers. J Med Toxicol. 2007 Mar;3(1):25-30. Using the modified electrometric method, various percentages of cholinesterase inhibitions in the plasma, erythrocytes, and whole blood were detected after in vitro addition of the organophosphate insecticides (chlorpyrifos and methidathion) and the insecticide (carbaryl) to the reaction mixtures. |
47(0,1,2,12) | Details |
| 6408651 | Ruppert PH, Cook LL, Dean KF, Reiter LW: Acute behavioral toxicity of carbaryl and propoxur in adult rats. Pharmacol Biochem Behav. 1983 Apr;18(4):579-84. Motor activity and neuromotor function were examined in adult CD rats exposed to either carbaryl or propoxur, and behavioral effects were compared with the time course of cholinesterase inhibition. |
45(0,1,3,5) | Details |
| 8405782 | Nostrandt AC, Duncan JA, Padilla S: A modified spectrophotometric method appropriate for measuring cholinesterase activity in tissue from carbaryl-treated animals. Fundam Appl Toxicol. 1993 Aug;21(2):196-203. |
38(0,1,1,8) | Details |
| 7481747 | Johnston G: The study of interactive effects of pollutants: a biomarker approach. Sci Total Environ. 1995 Oct 27;171(1-3):205-12. Biochemical biomarkers, such as inhibition of serum butyryl cholinesterase (BuChE) and brain acetyl cholinesterase (AChE), have been useful in studies of interactive effects of pesticides in birds. |
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| 18969806 | Solna R, Sapelnikova S, Skladal P, Winther-Nielsen M, Carlsson C, Emneus J, Ruzgas T: Multienzyme electrochemical array sensor for determination of phenols and pesticides. Talanta. 2005 Jan 30;65(2):349-57. The screen-printed four-electrode system was used as the amperometric transducer for determination of phenols and pesticides using immobilised tyrosinase, peroxidase, acetylcholinesterase and butyrylcholinesterase. The detection of and as well as of pesticides including carbaryl, heptenophos and fenitrothion was carried out in flow-through and steady state arrangements. |
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| 11718951 | Gordon CJ, Mack CM: Diurnal variation in thermoregulatory response to chlorpyrifos and carbaryl in the rat. Toxicology. 2001 Dec 14;169(2):93-105. It would be expected that the circadian temperature rhythm (CTR) as well as the circadian rhythms of other physiological processes would affect the efficacy of anticholinesterase (antiChE) insecticides. |
1(0,0,0,1) | Details |
| 985225 | Stone BF, Wilson JT, Youlton NJ: Linkage and dominance characteristics of genes for resistance to organophosphorus acaricides and allelic inheritance of decreased brain cholinesterase activity in three strains of the cattle tick, Boophilus microplus. Aust J Biol Sci. 1976 Jul;29(3):251-63. No F1 larval progeny from the following crossings were appreciably more resistant than their parents to these chemicals: R x B--bromophos ethyl and fenthion; B x M--carbaryl, chlorfenvinphos, chlorpyrifos, diazinon, dimethoate, ethion, fenthion and formothion; M x R--chlorfenvinphos, diazinon, dimethoate, ethion, formothion. |
1(0,0,0,1) | Details |
| 4625835 | Voitenko GA, Podliniaeva MA: [Toxicity and anticholinesterase action of some pesticides--derivatives of N-methyl and N-phenylcarbamic acids] Farmakol Toksikol. 1972 May-Jun;35(3):356-60. |
1(0,0,0,1) | Details |
| 17509940 | Ferrari A, Venturino A, Pechen de D'Angelo AM: Muscular and brain cholinesterase sensitivities to azinphos methyl and carbaryl in the juvenile rainbow trout Oncorhynchus mykiss. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Sep;146(3):308-13. Epub 2007 Apr 19. Juvenile rainbow trout were exposed to AzMe and carbaryl and the sensitivity of skeletal muscular cholinesterase (ChE) and the time course of inhibition and recovery were evaluated. |
37(0,1,2,2) | Details |
| 19879661 | Kristoff G, Guerrero NR, Cochon AC: Inhibition of cholinesterases and carboxylesterases of two invertebrate species, Biomphalaria glabrata and Lumbriculus variegatus, by the pesticide carbaryl. Aquat Toxicol. 2009 Oct 8. |
37(0,1,2,2) | Details |
| 2105088 | Robinson LR: Carbaryl poisoning and edrophonium: electrophysiologic changes. Arch Phys Med Rehabil. 1990 Jan;71(1):60-2. A case of poisoning with the insecticide carbaryl, a cholinesterase inhibitor, was studied using repetitive stimulation and edrophonium administration. |
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| 16704050 | Hopkins WA, Winne CT: Influence of body size on swimming performance of four species of neonatal natricine snakes acutely exposed to a cholinesterase-inhibiting pesticide. Environ Toxicol Chem. 2006 May;25(5):1208-13. In the present study, we compared the swimming performance of four species of natricine snakes acutely exposed to a formulation of carbaryl to determine whether neonatal body size or skin permeability influences responsiveness. |
3(0,0,0,3) | Details |
| 16989325 | Zdrazilova P, Stepankova S, Komersova A, Vranova M, Komers K, Cegan A: Kinetics of 13 new cholinesterase inhibitors. . Z Naturforsch C. 2006 Jul-Aug;61(7-8):611-7. |
3(0,0,0,3) | Details |
| 1642791 | Bhattacharya S, Ghosh P, Ghosh S, Ghosh N, Bhattacharya B, Halder P: Acetylcholinesterase characteristics of termite queen exposed to anticholinesterase compounds. Biomed Environ Sci. 1992 Jun;5(2):178-83. Interestingly, the commercial formulations like Metacid-50 and Carbaryl are potent enough at 1 x 10 (-8) M to produce 50% in vitro inhibition of AChE of head and body regions within 15 min of preincubation. |
3(0,0,0,3) | Details |
| 17705658 | Aamodt S, Konestabo HS, Sverdrup LE, Gudbrandsen M, Reinecke SA, Reinecke AJ, Stenersen J: Recovery of cholinesterase activity in the earthworm Eisenia fetida Savigny following exposure to chlorpyrifos. Environ Toxicol Chem. 2007 Sep;26(9):1963-7. Carbaryl, which selectively inhibits E1, was used to discriminate the enzyme activities. |
3(0,0,0,3) | Details |
| 105407 | Goodwin N, Bach F, Wingfield SE: Cholinesterase-inhibiting pesticides. S Afr Med J. 1978 Oct 14;54(16):637. |
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| 15683833 | Ferrari A, Anguiano OL, Soleno J, Venturino A, Pechen de D'Angelo AM: Different susceptibility of two aquatic vertebrates (Oncorhynchus mykiss and Bufo arenarum) to azinphos methyl and carbaryl. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Dec;139(4):239-43. |
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| 1981345 | Ardizzone C, Krokos H, Lippe C: Actions of carbaryl on the ionic transport across the isolated skin of Rana esculenta. Comp Biochem Physiol C. 1990;97(1):49-51. |
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| 15378568 | Reuveny H, Cohen E: Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). Arch Insect Biochem Physiol. 2004 Oct;57(2):92-100. Of the three carbamates examined, only carbaryl was inhibitory at the mM range while pirimicarb and aldicarb were inactive. |
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